Effects of Platelet-Rich Fibrin on Palatal Wound Healing After Free Gingival Graft Harvesting: A Comparative Randomized Controlled Clinical Trial

被引:56
作者
Ozcan, Mustafa [1 ]
Ucak, Onur [1 ]
Alkaya, Bahar [1 ]
Keceli, Seray [1 ]
Seydaoglu, Gulsah [2 ]
Haytac, M. Cenk [1 ]
机构
[1] Cukurova Univ, Dept Periodontol, Adana, Turkey
[2] Cukurova Univ, Dept Biostat, Adana, Turkey
关键词
SUBEPITHELIAL CONNECTIVE-TISSUE; DONOR-SITE; THROMBOSPONDIN-1; RECESSION; DEFECTS; SHRINKAGE; MEMBRANE; COVERAGE;
D O I
10.11607/prd.3226
中图分类号
R78 [口腔科学];
学科分类号
1003 ;
摘要
This study was conducted to evaluate the effects of platelet-rich fibrin (PRF) on palatal wound healing after free gingival graft (FGG) harvesting. A total of 125 patients were randomized after FGG: PRF with butyl-cyanoacrylate (BC) adhesive (PRF group; n = 42), BC adhesive alone (BC group; n = 42), and sterile wet gauze compression (WG group; n = 41). Bleeding, pain, epithelialization, feeding habits, and sensation scores were recorded for different time points. Statistically significant differences were found for all parameters in favor of the PRF group (P = .0001). PRF may provide significant benefits for wound healing parameters and patients' postoperative course after palatal graft harvesting.
引用
收藏
页码:E270 / E278
页数:9
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