Antiphosphatidylethanolamine antibody as a marker of antiphospholipid syndrome?

被引:1
作者
Yelnik, Cecile Marie [1 ]
Dubucquoi, Sylvain [2 ]
Houfflin-Debarge, Veronique [3 ]
Lambert, Marc [1 ]
机构
[1] CHRU Lille, Hop Huriez, Serv Med Interne & Explorat Vasc, F-59037 Lille, France
[2] CHRU Lille, Inst Immunol, Ctr Biol Pathol Genet Med, F-59037 Lille, France
[3] CHRU Lille, Matern Jeanne de Flandres, Serv Pathol Obstet, F-59037 Lille, France
来源
PRESSE MEDICALE | 2015年 / 44卷 / 03期
关键词
SYSTEMIC-LUPUS-ERYTHEMATOSUS; PHOSPHATIDYLETHANOLAMINE APE; PREGNANCY LOSS; THROMBOSIS; AUTOANTIBODIES; RECOGNIZE; DIAGNOSIS; FAILURE; TESTS; ELISA;
D O I
10.1016/j.lpm.2014.06.033
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Antibody to phosphatidylethanolamine (aPE) are observed in thrombotic or obstetric manifestations suggestive of antiphospholipid syndrome (APS). aPE seem to be markers of thrombotic risk independent of conventional antiphospholipid antibodies (aPL). aPE assays are not standardized. There is no therapeutic recommendation for isolated aPE patients with thromboticor obstetric events. Prospective studies have to be carried to better define the therapeutic management of these patients. Value of aPE in APS criteria is still not established.
引用
收藏
页码:284 / 291
页数:8
相关论文
共 33 条
[1]  
Balada E, 2001, SCAND J RHEUMATOL, V30, P235
[2]   Phosphatidylethanolamine critically supports internalization of cell-penetrating protein C inhibitor [J].
Baumgaertner, Petra ;
Geiger, Margarethe ;
Zieseniss, Susanne ;
Malleier, Julia ;
Huntington, James A. ;
Hochrainer, Karin ;
Bielek, Edith ;
Stoeckelhuber, Mechthild ;
Lauber, Kirsten ;
Scherfeld, Dag ;
Schwille, Petra ;
Waeldele, Katja ;
Beyer, Klaus ;
Engelmann, Bernd .
JOURNAL OF CELL BIOLOGY, 2007, 179 (04) :793-804
[3]   Influence of the phosphatidylethanolamine (PE) and bovine serum origins on anti-PE antibody detection by ELISA [J].
Berard, M ;
Boffa, MC .
THROMBOSIS RESEARCH, 1997, 85 (05) :439-442
[4]   The clinical value of testing for antibodies to phosphatidylethanolamine (aPE) in patients with systemic lupus erythematosus (SLE) [J].
Bertolaccini, M. L. ;
Murru, V. ;
Sciascia, S. ;
Sanna, G. ;
Khamashta, M. A. .
THROMBOSIS RESEARCH, 2012, 130 (06) :914-918
[5]   'Non-criteria' aPL tests: report of a task force and preconference workshop at the 13th International Congress on Antiphospholipid Antibodies, Galveston, TX, USA, April 2010 [J].
Bertolaccini, M. L. ;
Amengual, O. ;
Atsumi, T. ;
Binder, W. L. ;
de laat, B. ;
Forastiero, R. ;
Kutteh, W. H. ;
Lambert, M. ;
Matsubayashi, H. ;
Murthy, V. ;
Petri, M. ;
Rand, J. H. ;
Sanmarco, M. ;
Tebo, A. E. ;
Pierangeli, S. S. .
LUPUS, 2011, 20 (02) :191-205
[6]  
Bertolaccini ML, 1998, BRIT J RHEUMATOL, V37, P1229
[7]  
Gonzales-Portillo F, 2001, J Stroke Cerebrovasc Dis, V10, P222, DOI 10.1053/jscd.2001.29818
[8]  
Gris JC, 2000, THROMB HAEMOSTASIS, V84, P228
[9]   Laboratory Evaluation of Antiphospholipid Antibodies in Patients With Venous Thromboembolism [J].
Hirmerova, J. ;
Ulcova-Gallova, Z. ;
Seidlerova, J. ;
Filipovsky, J. ;
Bibkova, K. ;
Micanova, Z. ;
Mayer, O., Jr. .
CLINICAL AND APPLIED THROMBOSIS-HEMOSTASIS, 2010, 16 (03) :318-325
[10]   Seronegative antiphospholipid syndrome [J].
Hughes, GRV ;
Khamashta, MA .
ANNALS OF THE RHEUMATIC DISEASES, 2003, 62 (12) :1127-1127