Sensing and amplification of oligonucleotide-DNA interactions by means of impedance spectroscopy: a route to a Tay-Sachs sensor

被引：184

作者：

Bardea, A ^{[1
]}

Patolsky, F ^{[1
]}

Dagan, A ^{[1
]}

Willner, I ^{[1
]}

机构：

[1] Hebrew Univ Jerusalem, Inst Chem, IL-91904 Jerusalem, Israel

来源：

CHEMICAL COMMUNICATIONS | 1999年 / 01期

关键词：

D O I：

10.1039/a808319c

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A three-component oligonucleotide/DNA layered assembly on a An-electrode acts as a specific biosensor for the analysis of the Tay-Sachs mutant by means of Faradaic impedance spectroscopy.

引用

页码：21 / 22

页数：2

共 5 条

[1] Enzyme-linked amplified electrochemical sensing of oligonucleotide-DNA interactions by means of the precipitation of an insoluble product and using impedance spectroscopy
Patolsky, F
Katz, E
Bardea, A
Willner, I
LANGMUIR, 1999, 15 (11) : 3703 - 3706
[2] Amplified electronic transduction of oligonucleotide interactions: novel routes for Tay-Sachs biosensors
Bardea, A
Dagan, A
Willner, I
ANALYTICA CHIMICA ACTA, 1999, 385 (1-3) : 33 - 43
[3] Amplified microgravimetric quartz crystal-microbalance analyses of oligonucleotide complexes: a route to a Tay-Sachs biosensor device
Bardea, A
Dagan, A
Ben-Dov, I
Amit, B
Willner, I
CHEMICAL COMMUNICATIONS, 1998, (07) : 839 - 840
[4] ALLELE-SPECIFIC AMPLIFICATION OF GENOMIC DNA FOR DETECTION OF DELETION MUTATIONS - IDENTIFICATION OF A FRENCH-CANADIAN TAY-SACHS MUTATION
KAPLAN, F
BOULAY, B
BAYLERAN, J
HECHTMAN, P
JOURNAL OF INHERITED METABOLIC DISEASE, 1991, 14 (05) : 707 - 714
[5] Liposomes labeled with biotin and horseradish peroxidase: A probe for the enhanced amplification of antigen-antibody or oligonucleotide-DNA sensing processes by the precipitation of an insoluble product on electrodes
Alfonta, L
Singh, AK
Willner, I
ANALYTICAL CHEMISTRY, 2001, 73 (01) : 91 - 102

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