Current Use of and Trends in Hematopoietic Cell Transplantation in the United States

被引：381

作者：

D'Souza, Anita ^{[1
,2
]}

Fretham, Caitrin ^{[1
,3
]}

Lee, Stephanie J. ^{[1
,4
,5
]}

Arora, Mukta ^{[1
,6
]}

Brunner, Janet ^{[1
]}

Chhabra, Saurabh ^{[1
,2
]}

Devine, Steven ^{[1
,3
]}

Eapen, Mary ^{[1
,2
]}

Hamadani, Mehdi ^{[1
,2
]}

Hari, Parameswaran ^{[1
,2
]}

Pasquini, Marcelo C. ^{[1
,2
]}

Perez, Waleska ^{[1
]}

Phelan, Rachel A. ^{[1
,2
]}

Riches, Marcie L. ^{[1
,7
]}

Rizzo, J. Douglas ^{[1
,2
]}

Saber, Wael ^{[1
,2
]}

Shaw, Bronwen E. ^{[1
,2
]}

Spellman, Stephen R. ^{[1
,3
]}

Steinert, Patricia ^{[1
]}

Weisdorf, Daniel J. ^{[1
]}

Horowitz, Mary M. ^{[1
,2
]}

机构：

[1] Ctr Int Blood & Marrow Transplant Res, Milwaukee, WI USA

[2] Med Coll Wisconsin, Dept Med, Milwaukee, WI 53225 USA

[3] Natl Marrow Donor Program, Minneapolis, MN USA

[4] Fred Hutchinson Canc Res Ctr, 1124 Columbia St, Seattle, WA 98104 USA

[5] Univ Washington, Seattle, WA 98195 USA

[6] Univ Minnesota, Minneapolis, MN USA

[7] Univ N Carolina, Chapel Hill, NC 27515 USA

来源：

BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION | 2020年 / 26卷 / 08期

关键词：

Hematopoietic cell transplantation; Activity; Summary slides;

D O I：

10.1016/j.bbmt.2020.04.013

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Hematopoietic cell transplantation (HCT) is a well-established treatment to control and/or cure many malignant and nonmalignant diseases involving the hematopoietic system and some solid tumors. We report information about HCT procedures performed in the United States in 2018 and analyze trends and outcomes of HCT as reported to the Center for International Blood and Marrow Transplant Research (CIBMTR). Overall, compared with 2017, the number of allogeneic HCTs performed in the United States increased by 1%, and the number of autologous HCTs decreased by 5%. Key findings are fewer autologous HCTs performed for non-Hodgkin lymphoma and increasing numbers of haploidentical HCTs, nearly all of which use post-transplantation cyclophosphamide for graft-versus-host disease prophylaxis. There is a continuing increase in HCT in adults age >70 years, particularly for acute myelogenous leukemia and myelodysplastic syndromes. Survival rates by disease, disease stage, donor type, and age are presented. This report, prepared annually by the CIBMTR, provides a snapshot of current transplant activity in the United States. (C) 2020 American Society for Transplantation and Cellular Therapy. Published by Elsevier Inc.

引用

页码：E177 / E182

页数：6

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