Autoimmune Encephalitis in Children

被引:3
作者
Papetti, Laura [1 ]
Salfa, Irene [1 ]
Vigevano, Federico [1 ]
Valeriani, Massimiliano [1 ]
机构
[1] Bambino Gesu Childrens Hosp Rome, Div Child Neurol, Dept Neurosci, Rome, Italy
关键词
autoimmune encephalitis; antibodies; childhood; NMDA-RECEPTOR ENCEPHALITIS; POTASSIUM CHANNEL ANTIBODIES; VOLTAGE-GATED POTASSIUM; DISSEMINATED ENCEPHALOMYELITIS; HASHIMOTO ENCEPHALOPATHY; DIFFERENTIAL-DIAGNOSIS; CASE SERIES; SEIZURES; SPECTRUM; DISORDERS;
D O I
10.1055/s-0037-1620267
中图分类号
R51 [传染病];
学科分类号
100401 ;
摘要
Autoimmune encephalitis (AIE) can produce a very wide range of neuropsychiatric symptoms. A major challenge in diagnosis is that different symptoms may appear at different times and different levels of intensity, so the disease may mimic many other disorders. Pathogenesis is likely to be mediated by antibodies (Abs) to CNS proteins. This article focuses on recent clinical advances, newly characterized Abs, and treatment approaches to these disorders.
引用
收藏
页码:6 / 10
页数:5
相关论文
共 58 条
[1]   Unexplained seizures, confusion or hallucinations: think Hashimoto encephalopathy [J].
Alink, Jorien ;
de Vries, Tjalling W. .
ACTA PAEDIATRICA, 2008, 97 (04) :451-453
[2]   Autoimmune encephalitis as differential diagnosis of infectious encephalitis [J].
Armangue, Thais ;
Leypoldt, Frank ;
Dalmau, Josep .
CURRENT OPINION IN NEUROLOGY, 2014, 27 (03) :361-368
[3]   Neuromyelitis optica-IgG in childhood inflammatory demyelinating CNS disorders [J].
Banwell, B. ;
Tenembaum, S. ;
Lennon, V. A. ;
Ursell, E. ;
Kennedy, J. ;
Bar-Or, A. ;
Weinshenker, B. G. ;
Lucchinetti, C. F. ;
Pittock, S. J. .
NEUROLOGY, 2008, 70 (05) :344-352
[4]   Anti-NMDA receptor encephalitis: an important differential diagnosis in psychosis [J].
Barry, Helen ;
Hardiman, Orla ;
Healy, Daniel G. ;
Keogan, Mary ;
Moroney, Joan ;
Molnar, Peter P. ;
Cotter, David R. ;
Murphy, Kieran C. .
BRITISH JOURNAL OF PSYCHIATRY, 2011, 199 (06) :508-509
[5]   Clinical and neuroradiological differences of paediatric acute disseminating encephalomyelitis with and without antibodies to the myelin oligodendrocyte glycoprotein [J].
Baumann, M. ;
Sahin, K. ;
Lechner, C. ;
Hennes, E. M. ;
Schanda, K. ;
Mader, S. ;
Karenfort, M. ;
Selch, C. ;
Haeusler, M. ;
Eisenkoelbl, A. ;
Salandin, M. ;
Gruber-Sedlmayr, U. ;
Blaschek, A. ;
Kraus, V. ;
Leiz, S. ;
Finsterwalder, J. ;
Gotwald, T. ;
Kuchukhidze, G. ;
Berger, T. ;
Reindl, M. ;
Rostasy, K. .
JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY, 2015, 86 (03) :265-272
[6]   Children with multiphasic disseminated encephalomyelitis and antibodies to the myelin oligodendrocyte glycoprotein (MOG): Extending the spectrum of MOG antibody positive diseases [J].
Baumann, Matthias ;
Hennes, Eva-Maria ;
Schanda, Kathrin ;
Karenfort, Michael ;
Kornek, Barbara ;
Seidl, Rainer ;
Diepold, Katharina ;
Lauffer, Heinz ;
Marquardt, Iris ;
Strautmanis, Jurgis ;
Syrbe, Steffen ;
Vieker, Silvia ;
Hoeftberger, Romana ;
Reindl, Markus ;
Rostasy, Kevin .
MULTIPLE SCLEROSIS JOURNAL, 2016, 22 (14) :1821-1829
[7]  
BRAIN L, 1966, LANCET, V2, P512
[8]   Potassium channel antibodies in two patients with reversible limbic encephalitis [J].
Buckley, C ;
Oger, J ;
Clover, L ;
Tüzün, E ;
Carpenter, K ;
Jackson, M ;
Vincent, A .
ANNALS OF NEUROLOGY, 2001, 50 (01) :73-78
[9]   Hashimoto encephalopathy - Syndrome or myth? [J].
Chong, JY ;
Rowland, LP ;
Utiger, RD .
ARCHIVES OF NEUROLOGY, 2003, 60 (02) :164-171
[10]   Clinical experience and laboratory investigations in patients with anti-NMDAR encephalitis [J].
Dalmau, Josep ;
Lancaster, Eric ;
Martinez-Hernandez, Eugenia ;
Rosenfeld, Myrna R. ;
Balice-Gordon, Rita .
LANCET NEUROLOGY, 2011, 10 (01) :63-74