Automated system for the analysis of heart monophasic action Potentials

被引:8
作者
Tsalikakis, DG [1 ]
Fotiadis, DI [1 ]
Koletis, T [1 ]
Michalis, LK [1 ]
机构
[1] Univ Ioannina, Dept Comp Sci, Unit Med Technol & Intelligent Informat Syst, GR-45110 Ioannina, Greece
来源
COMPUTERS IN CARDIOLOGY 2003, VOL 30 | 2003年 / 30卷
关键词
D O I
10.1109/CIC.2003.1291160
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
In this paper we present an automated system, which can be used in real time for the analysis of heart monophasic action potentials (MAPs) in order to analyze the behaviour of the myocardium under pathological or normal conditions. The system can be described as a three-stage procedure. In the first stage MAPs are acquired using epicardiac electrodes or MAP Franz catheters and the noise is removed using a combination of notch and band pass filters. In the second stage several features of the signal are extracted. In the third stage statistical analysis is performed. The obtained results can be used for the assessment of the electrophysiological status of the atrial muscle, ventricular muscle, and the evaluation of the effects of antiarrhythmic drugs. The validation of the system indicated that it can provide with reliable information on the myocardium condition.
引用
收藏
页码:339 / 342
页数:4
相关论文
共 21 条
[1]   Dispersion of ventricular repolarization in the voltage domain [J].
Behrens, S ;
Li, CL ;
Knollmann, BC ;
Franz, MR .
PACE-PACING AND CLINICAL ELECTROPHYSIOLOGY, 1998, 21 (01) :100-107
[2]   Filtering of electromyogram artifacts from the electrocardiogram [J].
Christov, II ;
Daskalov, IK .
MEDICAL ENGINEERING & PHYSICS, 1999, 21 (10) :731-736
[3]   Correlation of repolarization of ventricular monophasic action potential with ECG in the murine heart [J].
Danik, S ;
Cabo, C ;
Chiello, C ;
Kang, S ;
Wit, AL ;
Coromilas, J .
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY, 2002, 283 (01) :H372-H381
[4]   Electrocardiogram signal preprocessing for automatic detection of QRS boundaries [J].
Daskalov, IK ;
Christov, II .
MEDICAL ENGINEERING & PHYSICS, 1999, 21 (01) :37-44
[5]   EFFECT OF CHANGES IN LOAD ON MONOPHASIC ACTION-POTENTIAL AND SEGMENT LENGTH OF PIG-HEART INSITU [J].
DEAN, JW ;
LAB, MJ .
CARDIOVASCULAR RESEARCH, 1989, 23 (10) :887-896
[6]   Development and evaluation of a fully automated monophasic action potential analysis program [J].
Dickenson, DR ;
Davis, DR ;
Beatch, GN .
MEDICAL & BIOLOGICAL ENGINEERING & COMPUTING, 1997, 35 (06) :653-660
[7]   Prolonged action potential durations, increased dispersion of repolarization, and polymorphic ventricular tachycardia in a mouse model of proarrhythmia [J].
Fabritz, L ;
Kirchhof, P ;
Franz, MR ;
Eckardt, L ;
Mönnig, G ;
Milberg, P ;
Breithardt, G ;
Haverkamp, W .
BASIC RESEARCH IN CARDIOLOGY, 2003, 98 (01) :25-32
[8]  
Franz M., 2000, MONOPHASIC ACTION PO
[9]   COMPUTER-ANALYSIS OF MONOPHASIC ACTION-POTENTIALS - MANUAL VALIDATION AND CLINICALLY PERTINENT APPLICATIONS [J].
FRANZ, MR ;
KIRCHHOF, PF ;
FABRITZ, CL ;
ZABEL, M .
PACE-PACING AND CLINICAL ELECTROPHYSIOLOGY, 1995, 18 (09) :1666-1678
[10]   Current status of monophasic action potential recording: theories, measurements and interpretations [J].
Franz, MR .
CARDIOVASCULAR RESEARCH, 1999, 41 (01) :25-40