Analgesic Use for Knee and Hip Osteoarthritis in Community-Dwelling Elders

被引:36
作者
Marcum, Zachary A. [1 ]
Perera, Subashan [3 ]
Donohue, Julie M. [4 ]
Boudreau, Robert M. [5 ]
Newman, Anne B. [5 ]
Ruby, Christine M. [6 ]
Studenski, Stephanie A. [7 ,8 ]
Kwoh, C. Kent [2 ,7 ,8 ]
Simonsick, Eleanor M. [9 ]
Bauer, Doug C. [10 ]
Satterfield, Suzanne [11 ]
Hanlon, Joseph T. [5 ,6 ,7 ,8 ]
机构
[1] Univ Pittsburgh, Sch Med, Dept Med Geriatr, Pittsburgh, PA 15213 USA
[2] Univ Pittsburgh, Sch Med, Dept Med Rheumatol & Clin Immunol, Pittsburgh, PA 15213 USA
[3] Univ Pittsburgh, Grad Sch Publ Hlth, Dept Biostat, Pittsburgh, PA 15213 USA
[4] Univ Pittsburgh, Grad Sch Publ Hlth, Dept Hlth Policy & Management, Pittsburgh, PA 15213 USA
[5] Univ Pittsburgh, Grad Sch Publ Hlth, Dept Epidemiol, Pittsburgh, PA 15213 USA
[6] Univ Pittsburgh, Sch Pharm, Dept Pharm & Therapeut, Pittsburgh, PA 15213 USA
[7] Vet Affairs Pittsburgh Healthcare Syst, Ctr Hlth Equ Res, Pittsburgh, PA USA
[8] Vet Affairs Pittsburgh Healthcare Syst, Geriatr Res Educ & Clin Ctr, Pittsburgh, PA USA
[9] NIA, Intramural Res Program, Baltimore, MD 21224 USA
[10] Univ Calif San Francisco, Sch Med, Dept Med Gen Internal Med, San Francisco, CA USA
[11] Univ Tennessee, Ctr Hlth Sci, Dept Prevent Med, Memphis, TN 38163 USA
基金
美国医疗保健研究与质量局;
关键词
Aged; Analgesic; Osteoarthritis; CARDIOVASCULAR-DISEASE INDICATORS; OLDER-ADULTS; HEALTH; PAIN; CARE; MANAGEMENT; RECOMMENDATIONS; PERFORMANCE; ARTHRITIS; OUTCOMES;
D O I
10.1111/j.1526-4637.2011.01249.x
中图分类号
R614 [麻醉学];
学科分类号
100217 ;
摘要
Objective. To examine the prevalence and correlates of non-opioid and opioid analgesic use and descriptively evaluate potential undertreatment in a sample of community-dwelling elders with symptomatic knee and/or hip osteoarthritis (OA). Design. Cross-sectional. Setting. Health, Aging, and Body Composition Study. Patients. Six hundred and fifty-two participants attending the year 6 visit (2002-03) with symptomatic knee and/or hip OA. Outcome Measures. Analgesic use was defined as taking >= 1 non-opioid and/or >= 1 opioid receptor agonist. Non-opioid and opioid doses were standardized across all agents by dividing the daily dose used by the minimum effective analgesic daily dose. Inadequate pain control was defined as severe/extreme OA pain in the past 30 days from a modified Western Ontario and McMaster Universities Osteoarthritis Index. Results. Just over half (51.4%) reported taking at least one non-opioid analgesic and approximately 10% was taking an opioid, most (88.5%) of whom also took a non-opioid. One in five participants (19.3%) had inadequate pain control, 39% of whom were using <1 standardized daily dose of either a non-opioid or opioid analgesic. In adjusted analyses, severe/extreme OA pain was significantly associated with both non-opioid (adjusted odds ratio [AOR] = 2.44; 95% confidence interval [95% CI] = 1.49-3.99) and opioid (AOR = 2.64; 95% CI = 1.26-5.53) use. Conclusions. Although older adults with severe/extreme knee and/or hip OA pain are more likely to take analgesics than those with less severe pain, a sizable proportion takes less than therapeutic doses and thus may be undertreated. Further research is needed to examine barriers to optimal analgesic use.
引用
收藏
页码:1628 / 1636
页数:9
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