Iridoid glycosides and phenolic glycosides from Holmskioldia sanguinea

Four new iridoids, 6-O-alpha-L-(2 "-O-trans-cinnamoyl)rhamnopyranosylcatalpol, 6-O-alpha-L-(3 "-O-trans-cinnamoyl)rhamnopyranosylcatalpol, 6-O-alpha-L-(4 "-O-trans-cinnamoyl)rhamnopyranosylcatalpol and 6-O-alpha-L-(4 "-O-cis-feruloyl)rhamnopyranosylcatalpol, along with three known monoacyl rhamnopyranosylcatalpol derivatives have been isolated from the aerial parts of Holmskioldia sanguinea. Catalpol was identified by GC and GC-MS analysis. Three known phenolic glycosides, isolated in small amounts, were identified as methyl salicylate glucoside, osmanthuside H, and icariside F-2. The structures were established by spectroscopic methods. The taxonomic significance of our results is discussed. (C) 1998 Elsevier Science Ltd. All rights reserved.