Chronic Cerebrospinal Venous Insufficiency and Multiple Sclerosis

被引：16

作者：

Bagert, Bridget A. ^{[1
]}

Marder, Ellen ^{[2
]}

Stueve, Olaf ^{[2
]}

机构：

[1] Ochsner Clin Fdn, Dept Neurol, New Orleans, LA 70115 USA

[2] Univ Texas SW Med Ctr Dallas, Dept Neurol & Neurotherapeut, Dallas, TX 75390 USA

来源：

ARCHIVES OF NEUROLOGY | 2011年 / 68卷 / 11期

关键词：

EPSTEIN-BARR-VIRUS; INFECTIOUS-MONONUCLEOSIS; IRON DEPOSITION; ASSOCIATION; FLOW; MS; PREGNANCY; FERRITIN; DISEASE; RISK;

D O I：

10.1001/archneurol.2011.179

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Chronic cerebrospinal venous insufficiency has recently been proposed to be etiologic to multiple sclerosis. Independent investigation into this theory during the past 2 years has not succeeded in verifying this relationship. A critical analysis of the scientific methods used in the original studies of chronic cerebrospinal venous insufficiency in multiple sclerosis reveals several methodological problems with regard to potential bias and confounding. The current evidence calls into question whether chronic cerebrospinal venous insufficiency in multiple sclerosis exists at all. Arch Neurol. 2011; 68(11): 1379-1384. Published online July 11, 2011. doi: 10.1001/archneurol.2011.179

引用

页码：1379 / 1384

页数：6

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