Combined microwave and ultrasound accelerated Knoevenagel-Doebner reaction in aqueous media: a green route to 3-aryl acrylic acids

被引：46
作者：
Peng, YQ [1 ]
Song, GH [1 ]
机构：
[1] E China Univ Sci & Technol, Inst Pesticides & Pharmaceut, Shanghai Key Lab Chem Biol, Shanghai 200237, Peoples R China
来源：
GREEN CHEMISTRY | 2003年 / 5卷 / 06期
关键词：
D O I：
10.1039/b310388a
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
The microwave and ultrasound combined aqueous Knoevenagel - Doebner reaction proves an efficient and eco- friendly route for preparing 3- aryl acrylic acids in good yields. This organic solvent- free protocol is valuable since rapid reaction rate, low energy consumption, waste minimization, simple operation and easier product work- up can be achieved.
引用
收藏
页码：704 / 706
页数：3
相关论文
共 29 条
[1]   Clean synthesis in water: uncatalysed preparation of ylidenemalononitriles [J].
Bigi, F ;
Conforti, ML ;
Maggi, R ;
Piccinno, A ;
Sartori, G .
GREEN CHEMISTRY, 2000, 2 (03) :101-103
[2]   HYDROPHOBIC EFFECTS ON SIMPLE ORGANIC-REACTIONS IN WATER [J].
BRESLOW, R .
ACCOUNTS OF CHEMICAL RESEARCH, 1991, 24 (06) :159-164
[3]   HETEROCYCLIC SYNTHESES WITH MALONYL CHLORIDE .4. PYRONODIOXINS FROM AN ENOLIC KETONE, DIKETONES, AND BENZALDEHYDE, AND A MODIFICATION OF DOEBNER CONDENSATION [J].
DAVIS, SJ ;
ELVIDGE, JA .
JOURNAL OF THE CHEMICAL SOCIETY, 1962, (SEP) :3550-&
[4]   Synthesis of sorbic acid [J].
Doebner, O .
BERICHTE DER DEUTSCHEN CHEMISCHEN GESELLSCHAFT, 1900, 33 :2140-2142
[5]  
Grieco P.A., 1998, Organic synthesis in water
[6]  
Johnson J.R., 1942, Organic Reactions, Org. React., V1, P210, DOI DOI 10.1002/0471264180.OR001.08
[7]  
Jones G., 1967, ORGANICREACTIONS, V15, P204, DOI [DOI 10.1002/0471264180.OR015.02, 10.1002/0471264180.or015.02]
[8]   SUBSTITUENT EFFECTS ON BROMODECARBOXYLATION REACTIONS [J].
KINGSBURY, CA ;
MAX, G .
JOURNAL OF ORGANIC CHEMISTRY, 1978, 43 (16) :3131-3139
[9]  
Li C. -J., 1997, ORGANIC REACTIONS AQ
[10]   Aqueous Barbier-Grignard type reaction: Scope, mechanism, and synthetic applications [J].
Li, CJ .
TETRAHEDRON, 1996, 52 (16) :5643-5668
123