Molecular signatures database (MSigDB) 3.0

被引:4549
作者
Liberzon, Arthur [1 ]
Subramanian, Aravind [1 ]
Pinchback, Reid [1 ]
Thorvaldsdottir, Helga [1 ]
Tamayo, Pablo [1 ]
Mesirov, Jill P. [1 ]
机构
[1] Broad Inst MIT & Harvard, Cambridge, MA 02142 USA
关键词
GENES;
D O I
10.1093/bioinformatics/btr260
中图分类号
Q5 [生物化学];
学科分类号
071010 ; 081704 ;
摘要
Motivation: Well-annotated gene sets representing the universe of the biological processes are critical for meaningful and insightful interpretation of large-scale genomic data. The Molecular Signatures Database (MSigDB) is one of the most widely used repositories of such sets. Results: We report the availability of a new version of the database, MSigDB 3.0, with over 6700 gene sets, a complete revision of the collection of canonical pathways and experimental signatures from publications, enhanced annotations and upgrades to the web site.
引用
收藏
页码:1739 / 1740
页数:2
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