Dilemmas in the Management of Osteoporosis in Younger Adults

被引:13
作者
Herath, Madhuni [1 ,2 ,3 ]
Cohen, Adi [4 ]
Ebeling, Peter R. [1 ,3 ]
Milat, Frances [1 ,2 ,3 ]
机构
[1] Monash Hlth, Dept Endocrinol, Clayton, Vic, Australia
[2] Hudson Inst Med Res, Ctr Endocrinol & Metab, 27-31 Wright St, Clayton, Vic 3168, Australia
[3] Monash Univ, Sch Clin Sci, Dept Med, Clayton, Vic, Australia
[4] Columbia Univ, Dept Med, Coll Phys & Surg, New York, NY USA
基金
澳大利亚国家健康与医学研究理事会; 英国医学研究理事会;
关键词
OSTEOPOROSIS; FRACTURE; BONE DENSITY; BONE QUALITY; PREMENOPAUSAL; YOUNG ADULT; FRACTURE RISK ASSESSMENT; FRACTURE PREVENTION; SCREENING; THERAPEUTICS; BONE-MINERAL DENSITY; GLUCOCORTICOID-INDUCED OSTEOPOROSIS; LACTATION-ASSOCIATED OSTEOPOROSIS; ADJUVANT ENDOCRINE THERAPY; CONNECTIVE-TISSUE DISEASE; PREMENOPAUSAL WOMEN; ZOLEDRONIC ACID; BREAST-CANCER; DOUBLE-BLIND; CYSTIC-FIBROSIS;
D O I
10.1002/jbm4.10594
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Osteoporosis in premenopausal women and men younger than 50 years is challenging to diagnose and treat. There are many barriers to optimal management of osteoporosis in younger adults, further enhanced by a limited research focus on this cohort. Herein we describe dilemmas commonly encountered in diagnosis, investigation, and management of osteoporosis in younger adults. We also provide a suggested framework, based on the limited available evidence and supported by clinical experience, for the diagnosis, assessment, and management of osteoporosis in this cohort. (c) 2021 The Authors. JBMR Plus published by Wiley Periodicals LLC on behalf of American Society for Bone and Mineral Research.
引用
收藏
页数:26
相关论文
共 176 条
  • [51] Comparative effects of teriparatide and risedronate in glucocorticoid-induced osteoporosis in men: 18-month results of the EuroGIOPs trial
    Glueer, Claus-C
    Marin, Fernando
    Ringe, Johann D.
    Hawkins, Federico
    Moericke, Ruediger
    Papaioannu, Nikolaos
    Farahmand, Parvis
    Minisola, Salvatore
    Martinez, Guillermo
    Nolla, Joan M.
    Niedhart, Christopher
    Guanabens, Nuria
    Nuti, Ranuccio
    Martin-Mola, Emilio
    Thomasius, Friederike
    Kapetanos, Georgios
    Pena, Jaime
    Graeff, Christian
    Petto, Helmut
    Sanz, Beatriz
    Reisinger, Andreas
    Zysset, Philippe K.
    [J]. JOURNAL OF BONE AND MINERAL RESEARCH, 2013, 28 (06) : 1355 - 1368
  • [52] Adjuvant endocrine therapy plus zoledronic acid in premenopausal women with early-stage breast cancer:: 5-year follow-up of the ABCSG-12 bone-mineral density substudy
    Gnant, Michael
    Mlineritsch, Brigitte
    Luschin-Ebengreuth, Gero
    Kainberger, Franz
    Kaessmann, Helmut
    Piswanger-Soelkner, Jutta Claudia
    Seifert, Michael
    Ploner, Ferdinand
    Menzel, Christian
    Dubsky, Peter
    Fitzal, Florian
    Bjelic-Radisic, Vesna
    Steger, Guenther
    Greil, Richard
    Marth, Christian
    Kubista, Ernst
    Samonigg, Hellmut
    Wohlmuth, Peter
    Mittlboeck, Martina
    Jakesz, Raimund
    [J]. LANCET ONCOLOGY, 2008, 9 (09) : 840 - 849
  • [53] Zoledronic acid prevents cancer treatment-induced bone loss in premenopausal women receiving adjuvant endocrine therapy for hormone-responsive breast cancer: A report from the Austrian Breast and Colorectal Cancer Study Group
    Gnant, Michael F. X.
    Mlineritsch, Brigitte
    Luschin-Ebengreuth, Gero
    Grampp, Stephan
    Kaessmann, Helmut
    Schmid, Marianne
    Menzel, Christian
    Piswanger-Soelkner, Jutta Claudia
    Galid, Arik
    Mittlboeck, Martina
    Hausmaninger, Hubert
    Jakesz, Raimund
    [J]. JOURNAL OF CLINICAL ONCOLOGY, 2007, 25 (07) : 820 - 828
  • [54] Aging and bone health in Singaporean Chinese pre-menopausal and postmenopausal women
    Goh, Victor Hng Hang
    Hart, William George
    [J]. MATURITAS, 2016, 89 : 16 - 21
  • [55] Functional Hypothalamic Amenorrhea: An Endocrine Society Clinical Practice Guideline
    Gordon, Catherine M.
    Ackerman, Kathryn E.
    Berga, Sarah L.
    Kaplan, Jay R.
    Mastorakos, George
    Misra, Madhusmita
    Murad, M. Hassan
    Santoro, Nanette F.
    Warren, Michelle P.
    [J]. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 2017, 102 (05) : 1413 - 1439
  • [56] Assessment and management of bone health in women with oestrogen receptor-positive breast cancer receiving endocrine therapy: position statement summary
    Grossmann, Mathis
    Ramchand, Sabashini K.
    Milat, Frances
    Vincent, Amanda
    Lim, Elgene
    Kotowicz, Mark A.
    Hicks, Jill
    Teede, Helena J.
    [J]. MEDICAL JOURNAL OF AUSTRALIA, 2019, 211 (05) : 224 - 229
  • [57] Güerri-Fernández R, 2017, JAIDS-J ACQ IMM DEF, V75, P322, DOI 10.1097/QAI.0000000000001396
  • [58] Effects of zoledronic acid on bone mineral density in premenopausal women receiving neoadjuvant or adjuvant therapies for HR+ breast cancer: the ProBONE II study
    Hadji, P.
    Kauka, A.
    Ziller, M.
    Birkholz, K.
    Baier, M.
    Muth, M.
    Bauer, M.
    [J]. OSTEOPOROSIS INTERNATIONAL, 2014, 25 (04) : 1369 - 1378
  • [59] Effects of alendronate and pamidronate on cultured rat metatarsal bones:: Failure to prevent dexamethasone-induced growth retardation
    Heino, Terhi J.
    Chagin, Andrei S.
    Takigawa, Masaharu
    Savendahl, Lars
    [J]. BONE, 2008, 42 (04) : 702 - 709
  • [60] Hembree WC, 2018, J CLIN ENDOCR METAB, V103, P699, DOI [10.1210/jc.2017-02548, 10.1210/jc.2017-01658]