Neuromuscular blocking agents for electroconvulsive therapy: a systematic review

被引：33

作者：

Mirzakhani, H. ^{[1
]}

Welch, C. A. ^{[2
]}

Eikermann, M. ^{[1
]}

Nozari, A. ^{[1
]}

机构：

[1] Harvard Univ, Dept Anaesthesia Crit Care & Pain Med, Sch Med, Massachusetts Gen Hosp, Boston, MA 02114 USA

[2] Harvard Univ, Dept Psychiat, Sch Med, Massachusetts Gen Hosp, Boston, MA 02114 USA

来源：

ACTA ANAESTHESIOLOGICA SCANDINAVICA | 2012年 / 56卷 / 01期

关键词：

NEUROLEPTIC MALIGNANT SYNDROME; POSTOPERATIVE RESIDUAL CURARIZATION; POSTANESTHESIA CARE-UNIT; RELAXANT BINDING-AGENT; CONVULSIVE SHOCK THERAPY; ANESTHETIC CONSIDERATIONS; SEVOFLURANE ANESTHESIA; ELDERLY-PATIENTS; DOSE-RESPONSE; TRAUMATIC COMPLICATIONS;

D O I：

10.1111/j.1399-6576.2011.02520.x

中图分类号：

R614 [麻醉学];

学科分类号：

100217 ;

摘要：

Electroconvulsive therapy (ECT) is the transcutaneous application of small electrical stimuli to the brain to induce generalised seizures for the treatment of selected psychiatric disorders. The clinical indications for ECT as an effective therapeutic modality have been considerably expanded since its introduction. Anaesthesia and neuromuscular blocking agents (NMBAs) are required to ensure patients safety during ECT. The optimal dose of muscle relaxant for ECT reduces muscle contractions without inducing complete paralysis. Slight residual motor convulsive activity is helpful in ascertaining that a seizure has occurred, while total paralysis prolongs the procedure unnecessarily. Suxamethonium is commonly used, but nondepolarising NMBAs are indicated in patients with certain comorbidities. In this review, we summarise current concepts of NMBA management for ECT.

引用

页码：3 / 16

页数：14

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