Synthesis of Pyrimido[4,5-e]tetrazolo[5,1-b][1,3,4]thiadiazepine as a Novel Fused Heterocyclic System

被引：0

作者：

Igei, Mansoore ^{[1
]}

Shiri, Ali ^{[1
]}

Bakavoli, Mehdi ^{[1
]}

Azizollahi, Hamid ^{[1
]}

机构：

[1] Ferdowsi Univ Mashhad, Dept Chem, Fac Sci, Mashhad 917751436, Razavi Khorasan, Iran

来源：

POLYCYCLIC AROMATIC COMPOUNDS | 2020年 / 40卷 / 02期

关键词：

2; 4-Dichloro-5-(chloromethyl)-6-methylpyrimidine; heterocyclization; pyrimidotetrazolothiadiazepine; SOLID SUPPORT SYNTHESIS; 5-HALO-1,2,3-THIADIAZOLES; DERIVATIVES;

D O I：

10.1080/10406638.2018.1458740

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Several derivatives of the novel fused seven-membered heterocyclic system of pyrimido[4,5-e]tetrazolo[5,1-b][1,3,4]thiadiazepine (5a-f) have been synthesized through the heterocyclization reaction of 2,4-dichloro-5-(chloromethyl)-6-methylpyrimidine (1) with sodium 1-amino-1H-tetrazole-5-thiolate (2) under basic conditions. Various derivatives were obtained via treatment with secondary amines.

引用

页码：535 / 539

页数：5

共 25 条

[1] Synthesis of Oxazolo[5,4-d][1,2,4]triazolo[4,3-a]pyrimidines as a New Class of Heterocyclic Compounds [J].

Akbarzadeh, Marzieh ;

Bakavoli, Mehdi ;

Eshghi, Hossein ;

Shiri, Ali .

JOURNAL OF HETEROCYCLIC CHEMISTRY, 2016, 53 (03) :832-839

[2] Synthesis of dihydrobenzo[b]pyrimido[4,5-e][1,4]thiazepines; derivatives of a novel ring system [J].

Akbarzadeh, Marzieh ;

Bakavoli, Mehdi ;

Eshghi, Hossein ;

Shiri, Ali ;

Tajabadi, Javad .

JOURNAL OF CHEMICAL RESEARCH, 2015, (09) :531-534

[3] Potentiality and Synthesis of O- and N-Heterocycles: Pd-Catalyzed Cyclocarbonylative Sonogashira Coupling as a Valuable Route to Phthalans, Isochromans, and Isoindolines [J].

Albano, Gianluigi ;

Aronica, Laura Antonella .

EUROPEAN JOURNAL OF ORGANIC CHEMISTRY, 2017, 2017 (48) :7204-7221

[4] Synthesis and Antibacterial Evaluations of New Pyridazino-[4,3-e][1,3,4]oxadiazines [J].

Bakavoli, Mehdi ;

Rahimizadeh, Mohammad ;

Shiri, Ali ;

Eshghi, Hossein ;

Pordeli, Parvaneh ;

Pordel, Mehdi ;

Nikpour, Mohsen .

JOURNAL OF HETEROCYCLIC CHEMISTRY, 2011, 48 (01) :149-152

[5]

Bavage S. B., 2011, SYNTHESIS 1 2 4 TRIA

[6] A facile synthesis of benzo[4,5]imidazo[2,1-b]pyrimido[5,4-f][1,3,4]thiadiazepines [J].

Brukstus, A ;

Melamedaite, D ;

Tumkevicius, S .

SYNTHETIC COMMUNICATIONS, 2000, 30 (20) :3719-3730

[7] Microwave enhanced solid support synthesis of fluorine containing benzopyrano-triazolo-thiadiazepines as potent anti-fungal agents [J].

Dandia, A ;

Singh, R ;

Khaturia, S .

BIOORGANIC & MEDICINAL CHEMISTRY, 2006, 14 (05) :1303-1308

[8] Synthesis, X-ray and Fluorescence Characteristics of Pyrimido[5,4-e]thiazolo[3,2-a]pyrimidine as a Novel Heterocyclic System [J].

Ebrahimpour, Zahra ;

Bakavoli, Mehdi ;

Shiri, Ali ;

Seyedi, Seyed Mohammad ;

Asghari, Tayebe ;

Mague, Joel T. .

JOURNAL OF FLUORESCENCE, 2017, 27 (03) :1183-1190

[9] Synthesis of Some New Benzo[b][1,4]diazepine Based Heterocycles [J].

El-Azab, Islam H. .

JOURNAL OF HETEROCYCLIC CHEMISTRY, 2013, 50 :E178-E188

[10] Pyrimido[5,4-e]tetrazolo[5,1-b][1,3,4] thiadiazines as a new heterocyclic system [J].

Eshghi, Hossein ;

Rahimizadeh, Mohammad ;

Saberi, Sattar ;

Abnous, Khalil ;

Bakavoli, Mehdi .

JOURNAL OF CHEMICAL RESEARCH, 2013, (09) :553-555

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