Macroscopic loop formation in circular DNA denaturation

被引:6
|
作者
Kabakcioglu, Alkan [1 ]
Bar, Amir [2 ,3 ]
Mukamel, David [2 ]
机构
[1] Koc Univ, Dept Phys, TR-34450 Istanbul, Turkey
[2] Weizmann Inst Sci, Dept Phys Complex Syst, IL-76100 Rehovot, Israel
[3] Weizmann Inst Sci, Dept Comp Sci & Appl Math, IL-76100 Rehovot, Israel
来源
PHYSICAL REVIEW E | 2012年 / 85卷 / 05期
关键词
NONLINEAR MODEL; TRANSITIONS; HELIX; FORCE;
D O I
10.1103/PhysRevE.85.051919
中图分类号
O35 [流体力学]; O53 [等离子体物理学];
学科分类号
070204 ; 080103 ; 080704 ;
摘要
The statistical mechanics of DNA denaturation under fixed linking number is qualitatively different from that of unconstrained DNA. Quantitatively different melting scenarios are reached from two alternative assumptions, namely, that the denatured loops are formed at the expense of (i) overtwist or (ii) supercoils. Recent work has shown that the supercoiling mechanism results in a picture similar to Bose-Einstein condensation where a macroscopic loop appears at T-c and grows steadily with temperature, while the nature of the denatured phase for the overtwisting case has not been studied. By extending an earlier result, we show here that a macroscopic loop appears in the overtwisting scenario as well. We calculate its size as a function of temperature and show that the fraction of the total sum of microscopic loops decreases above T-c, with a cusp at the critical point.
引用
收藏
页数:4
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