Weighing in on Heart Failure: The Role of SERCA2a SUMOylation

被引:11
作者
Schwartz, Robert J. [1 ,2 ]
Yeh, Edward T. H. [3 ]
机构
[1] Univ Houston, Dept Biol & Biochem, Locat UH Sci Ctr 466, Houston, TX 77204 USA
[2] Texas Heart Inst, Stem Cell Lab, Houston, TX 77025 USA
[3] Dept Cardiol, Houston, TX 77030 USA
关键词
SARCOPLASMIC-RETICULUM;
D O I
10.1161/RES.0b013e318246f187
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Heart failure is a growing problem but a recent report in Nature provides new insights into the role of post-translational modification of SERCA2a by SUMOylation. The enhanced benefits of SUMOylation may provide new therapeutic venues for the treatment of heart failure.
引用
收藏
页码:198 / 199
页数:2
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