Gastrointestinal Complications of Intra-Abdominal Desmoid Tumors: A Case Report and Review of the Literature

被引：1

作者：

Morris, Darcy ^{[1
]}

Gonzalez, Raquel ^{[2
]}

Cook, Jane ^{[3
]}

Metts, Jonathan ^{[4
]}

Shaw, Peter ^{[4
]}

机构：

[1] Johns Hopkins All Childrens Hosp, Off Med Educ, St Petersburg, FL USA

[2] Johns Hopkins All Childrens Hosp, Div Pediat Surg, St Petersburg, FL USA

[3] Johns Hopkins All Childrens Hosp, Div Radiol, St Petersburg, FL USA

[4] Johns Hopkins All Childrens Hosp, Canc & Blood Disorders Inst, St Petersburg, FL 33701 USA

来源：

CASE REPORTS IN ONCOLOGY | 2022年 / 15卷 / 02期

关键词：

Desmoid tumor; Tumor perforation; Bowel obstruction; Case report; BETA-CATENIN; FIBROMATOSIS; PERFORATION;

D O I：

10.1159/000522441

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

A 15-year-old male with a mesenteric desmoid tumor and underlying familial adenomatous polyposis presented 2 weeks after initiating sorafenib with severe abdominal pain and chills and was found to have an acute abdomen. Exploratory laparotomy revealed a necrotic, ruptured tumor with impending small bowel obstruction. The patient was later able to resume sorafenib and experienced sustained a radiographic response. It is possible that sorafenib toxicity contributed to tumor rupture yet later provided clinical benefit. Here we review the gastrointestinal complications that are associated with intra-abdominal desmoid tumors and their therapies.

引用

页码：515 / 521

页数：7

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