Nickel-Catalyzed Stereoselective Arylboration of Unactivated Alkenes

被引：108

作者：

Logan, Kaitlyn M. ^{[1
]}

Sardini, Stephen R. ^{[1
]}

White, Sean D. ^{[1
]}

Brown, M. Kevin ^{[1
]}

机构：

[1] Indiana Univ, Dept Chem, 800 East Kirkwood Ave, Bloomington, IN 47405 USA

来源：

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY | 2018年 / 140卷 / 01期

关键词：

CROSS-COUPLING REACTIONS; BORYLATIVE EXO-CYCLIZATION; ENANTIOSELECTIVE ARYLBORATION; COPPER(I)-CATALYZED REACTION; REGIOSELECTIVE ARYLBORATION; 3-COMPONENT CARBOBORATION; ORGANOMETALLIC REAGENTS; COOPERATIVE CATALYSIS; SYNERGISTIC CATALYSIS; ASYMMETRIC-SYNTHESIS;

D O I：

10.1021/jacs.7b12160

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A Ni-catalyzed method for arylboration is disclosed. The method allows for highly stereoselective arylboration of unactivated alkenes. The reactions utilize a simple Ni-catalyst and work with a broad range of alkenes and aryl bromides. The products represent useful intermediates for chemical synthesis due to the versatility of the C-B bond. Preliminary mechanistic details of the method are also disclosed.

引用

页码：159 / 162

页数：4

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