A novel class of amide-derived air-stable P,O-ligands for Suzuki cross-coupling at low catalyst loading

被引：49

作者：

Dai, WM ^{[1
]}

Li, YN

Zhang, Y

Lai, KW

Wu, JL

机构：

[1] Zhejiang Univ, Dept Chem, Lab Asymmetr Catalysis & Synth, Hangzhou 310027, Peoples R China

[2] Hong Kong Univ Sci & Technol, Dept Chem, Kowloon, Hong Kong, Peoples R China

来源：

TETRAHEDRON LETTERS | 2004年 / 45卷 / 09期

关键词：

amides; phosphines; coupling reactions; aryl bromides;

D O I：

10.1016/j.tetlet.2003.12.142

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The benzamide-derived P,O-ligands efficiently promoted the Pd-catalyzed Suzuki cross-coupling reactions of aryl bromides with phenylboronic acid at 0.01 mol % of Pd loading at 60-80degreesC to form biaryls in excellent yields. A sterically hindered arylboronic acid gave a quantitative yield of the coupling product at 110degreesC with 1 mol % Pd. (C) 2004 Elsevier Ltd. All rights reserved.

引用

页码：1999 / 2001

页数：3