A novel class of amide-derived air-stable P,O-ligands for Suzuki cross-coupling at low catalyst loading

被引：49
作者：
Dai, WM [1 ]
Li, YN
Zhang, Y
Lai, KW
Wu, JL
机构：
[1] Zhejiang Univ, Dept Chem, Lab Asymmetr Catalysis & Synth, Hangzhou 310027, Peoples R China
[2] Hong Kong Univ Sci & Technol, Dept Chem, Kowloon, Hong Kong, Peoples R China
来源：
TETRAHEDRON LETTERS | 2004年 / 45卷 / 09期
关键词：
amides; phosphines; coupling reactions; aryl bromides;
D O I：
10.1016/j.tetlet.2003.12.142
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
The benzamide-derived P,O-ligands efficiently promoted the Pd-catalyzed Suzuki cross-coupling reactions of aryl bromides with phenylboronic acid at 0.01 mol % of Pd loading at 60-80degreesC to form biaryls in excellent yields. A sterically hindered arylboronic acid gave a quantitative yield of the coupling product at 110degreesC with 1 mol % Pd. (C) 2004 Elsevier Ltd. All rights reserved.
引用
收藏
页码：1999 / 2001
页数：3
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