Higher sensitivity of IL-6 deficient mice to chemical oxidative hepatotoxicity and in vivo protection by an IL-6 receptor IL-6 chimera

被引:0
|
作者
Katz, A [1 ]
Chebath, J [1 ]
Friedman, J [1 ]
Revel, M [1 ]
机构
[1] Weizmann Inst Sci, Dept Mol Genet, IL-76100 Rehovot, Israel
关键词
D O I
暂无
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
491
引用
收藏
页码:329 / 329
页数:1
相关论文
共 50 条
  • [1] Increased sensitivity of IL-6-deficient mice to carbon tetrachloride hepatotoxicity and protection with an IL-6 receptor IL-6 chimera
    Katz, A
    Chebath, J
    Friedman, J
    Revel, M
    CYTOKINES CELLULAR & MOLECULAR THERAPY, 1998, 4 (04) : 221 - 227
  • [2] IL-6 AND IL-6 RECEPTOR
    MURAKAMI, M
    HIRANO, T
    SEIKAGAKU, 1990, 62 (01): : 32 - 35
  • [3] The function of the soluble interleukin 6 (IL-6) receptor in vivo: Sensitization of human soluble IL-6 receptor transgenic mice towards IL-6 and prolongation of the plasma half-life of IL-6
    Peters, M
    Jacobs, S
    Ehlers, M
    Vollmer, P
    Mullberg, J
    Wolf, E
    Brem, G
    zumBuschenfelde, KHM
    RoseJohn, S
    JOURNAL OF EXPERIMENTAL MEDICINE, 1996, 183 (04): : 1399 - 1406
  • [4] Minimal Interleukin 6 (IL-6) Receptor Stalk Composition for IL-6 Receptor Shedding and IL-6 Classic Signaling
    Baran, Paul
    Nitz, Rebecca
    Groetzinger, Joachim
    Scheller, Juergen
    Garbers, Christoph
    JOURNAL OF BIOLOGICAL CHEMISTRY, 2013, 288 (21) : 14756 - 14768
  • [5] Interleukin-6 (IL-6) production by astrocytes: Autocrine regulation by IL-6 and the soluble IL-6 receptor
    Van Wagoner, NJ
    Oh, JW
    Repovic, P
    Benveniste, EN
    JOURNAL OF NEUROSCIENCE, 1999, 19 (13): : 5236 - 5244
  • [6] Differences in Wound Healing in Mice with Deficiency of IL-6 versus IL-6 Receptor
    McFarland-Mancini, Molly M.
    Funk, Holly M.
    Paluch, Andrew M.
    Zhou, Mingfu
    Giridhar, Premkumar Vummidi
    Mercer, Carol A.
    Kozma, Sara C.
    Drew, Angela F.
    JOURNAL OF IMMUNOLOGY, 2010, 184 (12): : 7219 - 7228
  • [7] IL-6 modulates TGF-β expression in skin from IL-6 deficient mice
    Luckett-Chastain, Lerin R.
    Smith, Mackenzie L.
    Gallucci, Randle M.
    JOURNAL OF IMMUNOLOGY, 2009, 182
  • [8] IL-6 AND IL-6 RECEPTOR IN HUMAN MULTIPLE-MYELOMA
    BERNARD, K
    REGIS, B
    EXPERIMENTAL HEMATOLOGY, 1993, 21 (08) : 1012 - 1012
  • [9] Overexpression of IL-6 and IL-6 receptor alpha in double transgenic mice: Effects on the CNS
    Weis, J
    Brunello, AG
    Franke, S
    Peters, M
    RoseJohn, S
    BRAIN PATHOLOGY, 1997, 7 (04) : 1114 - 1114
  • [10] Effects of IL-6 and IL-6 blockade on neutrophil function in vitro and in vivo
    Wright, Helen L.
    Cross, Andrew L.
    Edwards, Steven W.
    Moots, Robert J.
    RHEUMATOLOGY, 2014, 53 (07) : 1321 - 1331