Interneuron NMDA receptors change the gear of motor learning in the cerebellar machine

被引:1
作者
Fekete, Adam [1 ,2 ]
Wang, Lu-Yang [1 ,2 ]
机构
[1] SickKids Res Inst, Program Neurosci & Mental Hlth, Toronto, ON M5G 1X8, Canada
[2] Univ Toronto, Dept Physiol, Toronto, ON M5S 1A8, Canada
来源
JOURNAL OF PHYSIOLOGY-LONDON | 2019年 / 597卷 / 03期
基金
加拿大自然科学与工程研究理事会; 加拿大健康研究院;
关键词
Cerebellum; long-term depression; interneurone; NMDARs; nitric oxide;
D O I
10.1113/JP277376
中图分类号
Q189 [神经科学];
学科分类号
071006 ;
摘要
引用
收藏
页码:663 / 664
页数:2
相关论文
共 6 条
[1]   The cerebellar microcircuit as an adaptive filter: experimental and computational evidence [J].
Dean, Paul ;
Porrill, John ;
Ekerot, Carl-Fredrik ;
Jorntell, Henrik .
NATURE REVIEWS NEUROSCIENCE, 2010, 11 (01) :30-43
[2]  
Eccles JC, 1967, CEREBELLUM NEURONAL
[3]   Interneuronal NMDA receptors regulate long-term depression and motor learning in the cerebellum [J].
Kono, Maya ;
Kakegawa, Wataru ;
Yoshida, Kazunari ;
Yuzaki, Michisuke .
JOURNAL OF PHYSIOLOGY-LONDON, 2019, 597 (03) :903-920
[4]   Optogenetic Modulation and Multi-Electrode Analysis of Cerebellar Networks In Vivo [J].
Kruse, Wolfgang ;
Krause, Martin ;
Aarse, Janna ;
Mark, Melanie D. ;
Manahan-Vaughan, Denise ;
Herlitze, Stefan .
PLOS ONE, 2014, 9 (08)
[5]   The neuropsychiatry of the cerebellum - insights from the clinic [J].
Schmahmann, Jeremy D. ;
Weilburg, Jeffrey B. ;
Sherman, Janet C. .
CEREBELLUM, 2007, 6 (03) :254-267
[6]   Identification of a molecular locus for normalizing dysregulated GABA release from interneurons in the Fragile X brain [J].
Yang, Yi-Mei ;
Arsenault, Jason ;
Bah, Alaji ;
Krzeminski, Mickael ;
Fekete, Adam ;
Chao, Owen Y. ;
Pacey, Laura K. ;
Wang, Alex ;
Forman-Kay, Julie ;
Hampson, David R. ;
Wang, Lu-Yang .
MOLECULAR PSYCHIATRY, 2020, 25 (09) :2017-2035