Icarus: visualizer for de novo assembly evaluation

被引：93

作者：

Mikheenko, Alla ^{[1
]}

Valin, Gleb ^{[2
]}

Prjibelski, Andrey ^{[1
]}

Saveliev, Vladislav ^{[1
]}

Gurevich, Alexey ^{[1
]}

机构：

[1] St Petersburg State Univ, Inst Translat Biomed, Ctr Algorithm Biotechnol, St Petersburg 199034, Russia

[2] Russian Acad Sci, St Petersburg Acad Univ, Dept Math & Informat Technol, St Petersburg 194021, Russia

来源：

BIOINFORMATICS | 2016年 / 32卷 / 21期

关键词：

GENOME ASSEMBLIES; ALGORITHMS; GAUGE; TOOL;

D O I：

10.1093/bioinformatics/btw379

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

Data visualization plays an increasingly important role in NGS data analysis. With advances in both sequencing and computational technologies, it has become a new bottleneck in genomics studies. Indeed, evaluation of de novo genome assemblies is one of the areas that can benefit from the visualization. However, even though multiple quality assessment methods are now available, existing visualization tools are hardly suitable for this purpose. Here, we present Icarus-a novel genome visualizer for accurate assessment and analysis of genomic draft assemblies, which is based on the tool QUAST. Icarus can be used in studies where a related reference genome is available, as well as for non-model organisms. The tool is available online and as a standalone application.

引用

页码：3321 / 3323

页数：3

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