Assembly of Oil-Based Microcapsules Coated with Proanthocyanidins as a Novel Carrier for Hydrophobic Active Compounds

Proanthocyanidins are sustainable materials with amphiphilic characteristic, network-forming capacity, and health benefits, which give them possibility as encapsulating biomaterials. We found that proanthocyanidins from Chinese bayberry leaves and grape seeds (BLPs and GSPs) were able to encapsulate oil to form spherical microcapsules of controlled size and architecture. Microcapsules encapsulated with BLPs and GSPs (BMs and GMs) exhibited different physical stability when subjected to environmental stresses. BMs showed higher physical stability to environmental stresses than GMs. The proanthocyanidin shell could protect beta-carotene from chemical degradation. Subsequently, varied gastrointestinal behaviors of the microcapsules were observed in simulated digestion. GMs with low stability reduced the lipid digestion and beta-carotene bioaccessibility. BMs with high stability retarded lipid digestion but did not change the amount of hydrolyzed lipids and beta-carotene bioaccessibility. Our study demonstrates that BLPs rather than GSPs can be used alone as encapsulating material for protection and targeted delivery of lipophilic bioactive compounds.