An expedient synthesis of diversified pyrrolizines and indolizines

被引：39

作者：

Bashiardes, G ^{[1
]}

Safir, I ^{[1
]}

Barbot, F ^{[1
]}

Laduranty, J ^{[1
]}

机构：

[1] Univ Poitiers, SFA, Dept Chim, UMR 6514, F-86022 Poitiers, France

来源：

TETRAHEDRON LETTERS | 2004年 / 45卷 / 07期

关键词：

pyrrolizines indolizines diversity;

D O I：

10.1016/j.tetlet.2003.11.146

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A general and rapid synthesis of new families of pyrrolizines and indolizines in good overall yields via an intramolecular [3+2]cycloaddition reaction is described. Diversity of substitutions can be achieved by the appropriate choice of readily available starting materials. The experimental procedures are straightforward and are performed under neutral conditions. New syntheses are also described for the preparation of N-propargylic 2-amino-benzaldehydes and S-propargylic 2-thiobenzaldehydes. (C) 2003 Elsevier Ltd. All rights reserved.

引用

页码：1567 / 1570

页数：4

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