A silicon strip detector array for energy verification and quality assurance in heavy ion therapy

被引:6
作者
Debrot, Emily [1 ]
Newall, Matthew [1 ]
Guatelli, Susanna [1 ]
Petasecca, Marco [1 ]
Matsufuji, Naruhiro [2 ]
Rosenfeld, Anatoly B. [1 ]
机构
[1] Univ Wollongong, Ctr Med Radiat Phys, Wollongong, NSW 2500, Australia
[2] Natl Inst Radiol Sci, Res Ctr Charge Particle Therapy, Chiba, Japan
基金
澳大利亚研究理事会;
关键词
energy verification; heavy ion therapy; Monte Carlo; QA; silicon strip detector; SCANNING IRRADIATION; IONIZATION-CHAMBER; SYSTEM; DOSIMETRY; GEANT4; FILMS; BEAMS; HIMAC;
D O I
10.1002/mp.12736
中图分类号
R8 [特种医学]; R445 [影像诊断学];
学科分类号
1002 ; 100207 ; 1009 ;
摘要
Purpose: The measurement of depth dose profiles for range and energy verification of heavy ion beams is an important aspect of quality assurance procedures for heavy ion therapy facilities. The steep dose gradients in the Bragg peak region of these profiles require the use of detectors with high spatial resolution. The aim of this work is to characterize a one dimensional monolithic silicon detector array called the "serial Dose Magnifying Glass" (sDMG) as an independent ion beam energy and range verification system used for quality assurance conducted for ion beams used in heavy ion therapy. Methods: The sDMG detector consists of two linear arrays of 128 silicon sensitive volumes each with an effective size of 2mm x 50 mu m x 100 mu m fabricated on a p-type substrate at a pitch of 200 mu m along a single axis of detection. The detector was characterized for beam energy and range verification by measuring the response of the detector when irradiated with a 290 MeV/u C-12 ion broad beam incident along the single axis of the detector embedded in a PMMA phantom. The energy of the 12C ion beam incident on the detector and the residual energy of an ion beam incident on the phantom was determined from the measured Bragg peak position in the sDMG. Ad hoc Monte Carlo simulations of the experimental setup were also performed to give further insight into the detector response. Results: The relative response profiles along the single axis measured with the sDMG detector were found to have good agreement between experiment and simulation with the position of the Bragg peak determined to fall within 0.2 mm or 1.1% of the range in the detector for the two cases. The energy of the beam incident on the detector was found to vary less than 1% between experiment and simulation. The beam energy incident on the phantom was determined to be (280.9 +/- 0.8) MeV/u from the experimental and (280.9 +/- 0.2) MeV/u from the simulated profiles. These values coincide with the expected energy of 281 MeV/u. Conclusions: The sDMG detector response was studied experimentally and characterized using a Monte Carlo simulation. The sDMG detector was found to accurately determine the 12C beam energy and is suited for fast energy and range verification quality assurance. It is proposed that the sDMG is also applicable for verification of treatment planning systems that rely on particle range. (C) 2017 American Association of Physicists in Medicine
引用
收藏
页码:953 / 962
页数:10
相关论文
共 20 条
  • [1] GEANT4-a simulation toolkit
    Agostinelli, S
    Allison, J
    Amako, K
    Apostolakis, J
    Araujo, H
    Arce, P
    Asai, M
    Axen, D
    Banerjee, S
    Barrand, G
    Behner, F
    Bellagamba, L
    Boudreau, J
    Broglia, L
    Brunengo, A
    Burkhardt, H
    Chauvie, S
    Chuma, J
    Chytracek, R
    Cooperman, G
    Cosmo, G
    Degtyarenko, P
    Dell'Acqua, A
    Depaola, G
    Dietrich, D
    Enami, R
    Feliciello, A
    Ferguson, C
    Fesefeldt, H
    Folger, G
    Foppiano, F
    Forti, A
    Garelli, S
    Giani, S
    Giannitrapani, R
    Gibin, D
    Cadenas, JJG
    González, I
    Abril, GG
    Greeniaus, G
    Greiner, W
    Grichine, V
    Grossheim, A
    Guatelli, S
    Gumplinger, P
    Hamatsu, R
    Hashimoto, K
    Hasui, H
    Heikkinen, A
    Howard, A
    [J]. NUCLEAR INSTRUMENTS & METHODS IN PHYSICS RESEARCH SECTION A-ACCELERATORS SPECTROMETERS DETECTORS AND ASSOCIATED EQUIPMENT, 2003, 506 (03) : 250 - 303
  • [2] A two dimensional silicon detectors array for quality assurance in stereotactic radiotherapy: MagicPlate-512
    Aldosari, A. H.
    Petasecca, M.
    Espinoza, A.
    Newall, M.
    Fuduli, I.
    Porumb, C.
    Alshaikh, S.
    Alrowaili, Z. A.
    Weaver, M.
    Metcalfe, P.
    Carolan, M.
    Lerch, M. L. F.
    Perevertaylo, V.
    Rosenfeld, A. B.
    [J]. MEDICAL PHYSICS, 2014, 41 (09)
  • [3] Geant4 developments and applications
    Allison, J
    Amako, K
    Apostolakis, J
    Araujo, H
    Dubois, PA
    Asai, M
    Barrand, G
    Capra, R
    Chauvie, S
    Chytracek, R
    Cirrone, GAP
    Cooperman, G
    Cosmo, G
    Cuttone, G
    Daquino, GG
    Donszelmann, M
    Dressel, M
    Folger, G
    Foppiano, F
    Generowicz, J
    Grichine, V
    Guatelli, S
    Gumplinger, P
    Heikkinen, A
    Hrivnacova, I
    Howard, A
    Incerti, S
    Ivanchenko, V
    Johnson, T
    Jones, F
    Koi, T
    Kokoulin, R
    Kossov, M
    Kurashige, H
    Lara, V
    Larsson, S
    Lei, F
    Link, O
    Longo, F
    Maire, M
    Mantero, A
    Mascialino, B
    McLaren, I
    Lorenzo, PM
    Minamimoto, K
    Murakami, K
    Nieminen, P
    Pandola, L
    Parlati, S
    Peralta, L
    [J]. IEEE TRANSACTIONS ON NUCLEAR SCIENCE, 2006, 53 (01) : 270 - 278
  • [4] Recent developments in GEANT4
    Allison, J.
    Amako, K.
    Apostolakis, J.
    Arce, P.
    Asai, M.
    Aso, T.
    Bagli, E.
    Bagulya, A.
    Banerjee, S.
    Barrand, G.
    Beck, B. R.
    Bogdanov, A. G.
    Brandt, D.
    Brown, J. M. C.
    Burkhardt, H.
    Canal, Ph.
    Cano-Ott, D.
    Chauvie, S.
    Cho, K.
    Cirrone, G. A. P.
    Cooperman, G.
    Cortes-Giraldo, M. A.
    Cosmo, G.
    Cuttone, G.
    Depaola, G.
    Desorgher, L.
    Dong, X.
    Dotti, A.
    Elvira, V. D.
    Folger, G.
    Francis, Z.
    Galoyan, A.
    Garnier, L.
    Gayer, M.
    Genser, K. L.
    Grichine, V. M.
    Guatelli, S.
    Gueye, P.
    Gumplinger, P.
    Howard, A. S.
    Hrivnacova, I.
    Hwang, S.
    Incerti, S.
    Ivanchenko, A.
    Ivanchenko, V. N.
    Jones, F. W.
    Jun, S. Y.
    Kaitaniemi, P.
    Karakatsanis, N.
    Karamitrosi, M.
    [J]. NUCLEAR INSTRUMENTS & METHODS IN PHYSICS RESEARCH SECTION A-ACCELERATORS SPECTROMETERS DETECTORS AND ASSOCIATED EQUIPMENT, 2016, 835 : 186 - 225
  • [5] Two-dimensional and quasi-three-dimensional dosimetry of hadron and photon beams with the Magic Cube and the Pixel Ionization Chamber
    Cirio, R
    Garelli, E
    Schulte, R
    Amerio, S
    Boriano, A
    Bourhaleb, F
    Coutrakon, G
    Donetti, M
    Giordanengo, S
    Koss, P
    Madon, E
    Marchetto, F
    Nastasi, U
    Peroni, C
    Santuari, D
    Sardo, A
    Scielzo, G
    Stasi, M
    Trevisiol, E
    [J]. PHYSICS IN MEDICINE AND BIOLOGY, 2004, 49 (16) : 3713 - 3724
  • [6] Quality assurance of proton beams using a multilayer ionization chamber system
    Dhanesar, Sandeep
    Sahoo, Narayan
    Kerr, Matthew
    Taylor, M. Brad
    Summers, Paige
    Zhu, X. Ronald
    Poenisch, Falk
    Gillin, Michael
    [J]. MEDICAL PHYSICS, 2013, 40 (09)
  • [7] Multichannel Data Acquisition System comparison for Quality Assurance in external beam radiation therapy
    Fuduli, I.
    Newall, M. K.
    Espinoza, A. A.
    Porumb, C. S.
    Carolan, M.
    Lerch, M. L. F.
    Metcalfe, P.
    Rosenfeld, A. B.
    Petasecca, M.
    [J]. RADIATION MEASUREMENTS, 2014, 71 : 338 - 341
  • [8] Application of radiochromic film for quality assurance in the heavy-ion beam scanning irradiation system at HIMAC
    Hara, Y.
    Furukawa, T.
    Mizushima, K.
    Takeshita, E.
    Shirai, T.
    Nocla, K.
    [J]. NUCLEAR INSTRUMENTS & METHODS IN PHYSICS RESEARCH SECTION B-BEAM INTERACTIONS WITH MATERIALS AND ATOMS, 2014, 331 : 253 - 256
  • [9] Quality assurance at the heavy-ion therapy facility at GSI
    Heeg, P
    Hartmann, G
    Jäkel, O
    Karger, C
    Kraft, G
    [J]. STRAHLENTHERAPIE UND ONKOLOGIE, 1999, 175 (Suppl 2) : 36 - 38
  • [10] Development of treatment planning for scanning irradiation at HIMAC
    Inaniwa, Taku
    Furukawa, Takuji
    Sato, Shinji
    Tomitani, Takehiro
    Kobayashi, Masanao
    Minohara, Shnichi
    Noda, Koji
    Kanai, Tatsuaki
    [J]. NUCLEAR INSTRUMENTS & METHODS IN PHYSICS RESEARCH SECTION B-BEAM INTERACTIONS WITH MATERIALS AND ATOMS, 2008, 266 (10) : 2194 - 2198