Canine oral fibrosarcomas: a retrospective analysis of 65 cases (1998-2010)

被引：30

作者：

Gardner, H. ^{[1
]}

Fidel, J. ^{[2
]}

Haldorson, G. ^{[3
]}

Dernell, W. ^{[2
]}

Wheeler, B. ^{[2
]}

机构：

[1] Univ Florida, Dept Small Anim Clin Sci, Gainesville, FL USA

[2] Washington State Univ, Vet Teaching Hosp, Dept Vet Clin Sci, Pullman, WA 99164 USA

[3] Washington State Univ, Dept Vet Microbiol & Pathol, Pullman, WA 99164 USA

来源：

VETERINARY AND COMPARATIVE ONCOLOGY | 2015年 / 13卷 / 01期

关键词：

dogs; oral fibrosarcoma; radiation therapy; surgery; SOFT-TISSUE SARCOMAS; PARTIAL MANDIBULECTOMY; RADIATION-THERAPY; HIGH-GRADE; DOGS; RADIOTHERAPY; TUMORS; CHEMOTHERAPY; MAXILLA;

D O I：

10.1111/vco.12017

中图分类号：

S85 [动物医学（兽医学）];

学科分类号：

0906 ;

摘要：

The objective of this retrospective study was to report the outcome of treatment of canine oral fibrosarcomas (FSA) in relation to median survival and progression-free survival (PFS), and to report whether grade was prognostic in relation to median survival. Sixty-five dogs with oral FSA presented to the WSU VTH between June 1998 and March 2010. Significant predictors of median survival were location (P=0.0099), tumour size or oral stage (P=0.0312), type of surgery (P=0.0182), margins (P=0.0329) and grade (P=0.0251). Significant predictors of PFS were location (P=0.0177), and radiation protocol (P=0.0343). A combination of surgery and radiation was the strongest predictor of prolonged median survival (P=0.0183) and PFS (P=0.0263) at 505and 301days, respectively. Treatment of canine oral FSA with a combination of surgery and radiation therapy provided the longest median survivals.

引用

页码：40 / 47

页数：8

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