Learning from failure: congestive heart failure in the postgenomic age

被引：36

作者：

Benjamin, IJ

Schneider, MD

机构：

[1] Univ Utah, Ctr Hlth Sci, Dept Internal Med, Div Cardiol, Salt Lake City, UT 84132 USA

[2] Baylor Coll Med, Ctr Cardiovasc Dev, Dept Med, Houston, TX USA

[3] Baylor Coll Med, Dept Mol & Cellular Biol, Houston, TX USA

[4] Baylor Coll Med, Dept Mol Physiol & Biophys, Houston, TX 77030 USA

来源：

JOURNAL OF CLINICAL INVESTIGATION | 2005年 / 115卷 / 03期

关键词：

D O I：

10.1172/JCI200524477

中图分类号：

R-3 [医学研究方法]; R3 [基础医学];

学科分类号：

1001 ;

摘要：

The prognosis of heart failure is worse than that of most cancers, but new therapeutic interventions using stem and other cell-based therapies are succeeding in the fight against it, and old drugs, with new twists, are making a comeback. Genetically engineered animal models are driving insights into the molecular mechanisms that cause hearts to fail, accelerating drug discoveries, and inspiring cell-based therapeutic interventions for both acquired and inheritable cardiac diseases.

引用

页码：495 / 499

页数：5

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