Nitazoxanide - A review of its use in the treatment of gastrointestinal infections

被引:126
作者
Anderson, Vanessa R.
Curran, Monique P.
机构
[1] Wolters Kluwer Hlth, Adis, Auckland, New Zealand
[2] Wolters Kluwer Hlth, Conshohocken, PA USA
关键词
nitazoxanide; antiprotozoal; antihelminthic; tizoxanide; gastrointestinal infections; diarrhoea; pharmacodynamics; pharmacokinetics; therapeutic use tolerability;
D O I
10.2165/00003495-200767130-00015
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
Nitazoxanide (Alinia((R)), Daxon((R)), Dexidex((R)), Paramix((R)), Kidonax((R)), Colufase((R)), Annita((R))) has in vitro activity against a variety of microorganisms, including a broad range of protozoa and helminths. Nitazoxanide is effective in the treatment of protozoal and helminthic infections, including Cryptosporidium parvum or Giardia lamblia, in immunocompetent adults and children, and is generally well tolerated. Nitazoxanide is a first-line choice for the treatment of illness caused by C. parvum or G. lamblia infection in immunocompetent adults and children, and is an option to be considered in the treatment of illnesses caused by other protozoa and/or helminths.
引用
收藏
页码:1947 / 1967
页数:21
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