Propafenone Poisoning of a Female Adolescent After a Suicide Attempt

被引:6
作者
Keramari, Stergiani [1 ]
Poutoglidis, Alexandros [2 ]
Poutoglidou, Frideriki [3 ]
Kaiafa, Georgia [4 ]
Keramaris, Michael [5 ]
机构
[1] Aristotle Univ Thessaloniki, AHEPA Univ Hosp, Fac Med, Dept Paediat 2,Sch Hlth Sci, Thessaloniki, Greece
[2] G Papanikolaou Gen Hosp, Otorhinolaryngol Head & Neck Surg, Thessaloniki, Greece
[3] Aristotle Univ Thessaloniki, Fac Med, Sch Hlth Sci, Clin Pharmacol, Thessaloniki, Greece
[4] Aristotle Univ Thessaloniki, AHEPA Univ Hosp, Fac Med, Propaedeut Dept Internal Med 1,Sch Hlth Sci, Thessaloniki, Greece
[5] Gen Hosp Kastoria, Cardiol, Kastoria, Greece
关键词
propafenone; seizure; poisoning; antiarrhythmic agent; arrhythmia; PHARMACOKINETICS; THERAPY;
D O I
10.7759/cureus.16576
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Propafenone is an antiarrhythmic agent for the management of ventricular and supraventricular tachycardia and atrial fibrillation. Propafenone poisoning is rare but may be life-threatening due to drug-induced arrhythmias. Electrocardiographic changes in PR, QRS, and QT intervals have been recorded. We present a case of a 15-year-old female adolescent who developed arrhythmias and convulsions due to propafenone intoxication, in an attempt to commit suicide. The outcome of the case was a full recovery from the arrhythmias and the seizures. The aim of this article is to highlight the possibility of a lethal intoxication by a common antiarrhythmic drug. Our case aims to present our therapeutic strategy that relies mainly on close monitoring of patients and cardiac output support.
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页数:5
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