Palladium-catalyzed synthesis of 2-amino ketones from propargylic carbonates and secondary amines

被引：11
|
作者：
Cacchi, Sandro [1 ]
Fabrizi, Giancarlo [1 ]
Filisti, Eleonora [1 ]
Goggiamani, Antonella [1 ]
Iazzetti, Antonia [1 ]
Maurone, Loredana [2 ,3 ]
机构：
[1] Univ Roma La Sapienza, Dipartimento Chim & Tecnol Farm, I-00185 Rome, Italy
[2] Univ Tuscia, Dipartimento ABAC, I-01100 Viterbo, Italy
[3] Consorzio Univ La Chim Ambiente, I-01100 Viterbo, Italy
来源：
ORGANIC & BIOMOLECULAR CHEMISTRY | 2012年 / 10卷 / 24期
关键词：
ASYMMETRIC ALPHA-AMINATION; SILYL ENOL ETHERS; N-HYDROXYAMINO ACIDS; ENANTIOSELECTIVE SYNTHESIS; ELECTROPHILIC AMINATION; ONE-POT; ALDEHYDES; PROTEASOME; COMPLEXES; AMINOKETONES;
D O I：
10.1039/c2ob25670c
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A novel palladium-catalyzed approach to 2-amino ketones from arylpropargylic carbonates bearing neutral, electron-rich, and electron-poor aromatic rings and cyclic secondary amines containing useful functional groups such as cyano, chloro, and bromo substituents has been developed.
引用
收藏
页码：4699 / 4703
页数：5
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