Post-Operative Complications in Living Liver Donors: A Single-Center Experience in China

被引:14
作者
Sun, Zhongquan [1 ,2 ,3 ]
Yu, Zhiyong [1 ,2 ,3 ]
Yu, Songfeng [1 ,2 ,3 ]
Chen, Jihao [1 ]
Wang, Jingqiao [1 ]
Yang, Cheng [1 ]
Jin, Mengmeng [1 ]
Yan, Sheng [1 ,2 ,3 ]
Zhang, Mangli [1 ,2 ,3 ]
Zhang, Min [1 ,2 ,3 ]
Zheng, Shusen [1 ,2 ,3 ]
机构
[1] Zhejiang Univ, Sch Med, Affiliated Hosp 1, Div Hepatobiliary & Pancreat Surg,Dept Surg, Hangzhou 310003, Zhejiang, Peoples R China
[2] Minist Publ Hlth, Key Lab Combined Multiorgan Transplantat, Hangzhou, Zhejiang, Peoples R China
[3] Key Lab Organ Transplantat, Hangzhou, Zhejiang, Peoples R China
关键词
RIGHT HEPATECTOMY; TRANSPLANTATION; MORBIDITY; RESECTION; SAFETY; VOLUME;
D O I
10.1371/journal.pone.0135557
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
The gap between the growing demand for available organs and the cadaveric organs facilitates the adoption of living donor liver transplantation. We retrospectively identified and evaluated the post-operative complications as per the modified Clavien classification system in 152 living liver donors at at the First Affiliated Hospital, College of Medicine, Zhejiang University between December, 2006 and June, 2014. Post-operative complications were observed in 61 patients (40.1%) in the present study, but no mortality was reported. Complications developed in 58 (40.0%) right, 1 (33.3%) left, and 2 (66.7%) lateral left hepatectomy donors. The prevalence of re-operation was 1.3%. Grade I and II complications were observed in 38 (25.0%) and 11 (7.2%) donors, respectively. Grade IIIa complications developed in 9 (5.9%) donors and only 3 (2.0%) patients reported grade IIIb complications. The most common complication was pleural effusion that occurred in 31 (20.4%) donors. No significant prognostic baseline factor was identified in this study. In conclusion, living donors experienced various complications, which were usually mild and had a good prognosis.
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页数:11
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