Physics settings for using the Geant4 toolkit in proton therapy

被引：167
作者：
Jarlskog, Christina Zacharatou [1 ,2 ]
Paganetti, Harald [1 ,2 ]
机构：
[1] Massachusetts Gen Hosp, Dept Radiat Oncol, Boston, MA 02114 USA
[2] Harvard Univ, Sch Med, Boston, MA 02114 USA
来源：
IEEE TRANSACTIONS ON NUCLEAR SCIENCE | 2008年 / 55卷 / 03期
关键词：
Geant4; Monte Carlo; physics validation; proton therapy;
D O I：
10.1109/TNS.2008.922816
中图分类号：
TM [电工技术]; TN [电子技术、通信技术];
学科分类号：
0808 ; 0809 ;
摘要：
We simulated electromagnetic and nuclear processes induced by clinical proton beams in order to select the physics setting for the 8.1 version of the Geant4 toolkit. A modular physics list was constructed allowing for alternative processes and models to be invoked in the simulations. We validated the Monte Carlo by means of measured depth-dose distributions in water for 86 MeV and 209 MeV beams and measured longitudinal charge profiles in a stack of polyethylene absorbers (multilayer Faraday cup) for a 160 MeV beam. Best agreement between simulation and measurement was found for the standard electromagnetic and binary cascade models of Geant4.
引用
收藏
页码：1018 / 1025
页数：8
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