Condensed isoquinolines 27.: Synthesis and oxidation reactions of 5,13-dihydro-11H-isoquino[3,2-b]quinazolin-11-one

被引：3

作者：

Potikha, L. M. ^{[1
]}

Gutsul, R. M. ^{[1
]}

Turov, A. V. ^{[1
]}

Kovtunenko, V. A. ^{[1
]}

机构：

[1] Taras Shevchenko Kiev Natl Univ, UA-01033 Kiev, Ukraine

来源：

CHEMISTRY OF HETEROCYCLIC COMPOUNDS | 2008年 / 44卷 / 02期

关键词：

2-aminobenzylamine; 6,6 ']bi[isoquino[3,2-b]quinazoline; dibenzo[b,f][1,8]naphthyridine; isoquino[3,2-b]quinazoline; 2-(cyanomethyl)benzoic acid; oxidation; rearrangement;

D O I：

10.1007/s10593-008-0024-6

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Condensation of 2-(cyanomethyl)benzoic acid with 2-aminobenzylamine gave 6,11-dihydro-13H-isoquino[3,2-b]quinazolin-11-one. Its oxidation in nitrobenzene led to the formation of 5,13,5',13'-hexahydro[6,6']bi[isoquino[3,2-b]quinazoline]-11,11'-dione, but in dichlorobenzene in the presence of elemental sulfur and iodine it gave the rearrangement product 6H-dibenzo[b,f][1,8]naphthyridin-5-one.

引用

页码：208 / 213

页数：6

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