The effect of past use of injectable contraceptive on bone mineral density in malaysian postmenopausal women

被引：0
作者：
Mohammadi, Fatemeh [1 ]
Aizan, Hamid Tengku [1 ]
Nazri, Mohd Yazid [2 ]
Othman, Zanariah [3 ]
Mahmud, Rozi [4 ]
机构：
[1] Univ Putra Malaysia, Inst Gerontol, Serdang, Malaysia
[2] Univ Putra Malaysia, Fac Med & Hlth Sci, Dept Obstet & Gynecol, Serdang, Malaysia
[3] Univ Putra Malaysia, Fac Med & Hlth Sci, Dept Surg Orthoped Surg, Serdang, Malaysia
[4] Univ Putra Malaysia, Fac Med & Hlth Sci, Dept Imaging, Serdang, Malaysia
来源：
HEALTHMED | 2011年 / 5卷 / 05期
关键词：
Bone mineral density; Norethisterone enanthate; Injectable contraceptives; Osteoporosis; Postmenopausal; DEPOT-MEDROXYPROGESTERONE ACETATE; COMBINED ORAL-CONTRACEPTIVES; NORETHISTERONE ENANTHATE; HORMONAL CONTRACEPTION; OSTEOPOROSIS; ADOLESCENTS; COUNTRIES;
D O I：
暂无
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Background: It is known that bone mineral density (BMD) reduction can occur in women using injectable birth control methods. There is a dearth of data on the effect(s) on subsequent BMD of norethisterone enanthate (NET-EN), the two monthly injectable which is marketed as Unidepo in Malaysia. The objective of this study was to determine the bone status in postmenopausal women who used NET-EN for contraception in their reproductive years. Methodology: In a cross-sectional study, BMD in former users of Unidepo was compared with non-users. Quantitative ultrasounds were used to measure the calcaneal bone mass. Results: From a total of the 201 postmenopausal women, 133 individuals were former Unidepo users and 68 women were non-users. A significant difference was found in the BMD of Unidepo users who had used it after the age of 40 and non-users. Conclusion: The results suggest that bone loss in women who used Unidepo after age 40 and for a very long time is not completely reversible.
引用
收藏
页码：1187 / 1194
页数：8
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