Anti-inflammatory Activity of Pistacia lentiscus Essential Oil: Involvement of IL-6 and TNF-α

被引：0

作者：

Maxia, Andrea ^{[1
]}

Sanna, Cinzia ^{[1
]}

Frau, Maria Assunta ^{[1
]}

Piras, Alessandra ^{[2
]}

Karchuli, Manvendra Singh ^{[3
]}

Kasture, Veena ^{[3
]}

机构：

[1] Univ Cagliari, Dept Life & Environm Sci, Bot & Bot Garden Div, Cagliari, Italy

[2] Univ Cagliari, Dept Chem, Monserrato, Italy

[3] Pinnacle Biomed Res Inst, Bhopal, India

来源：

NATURAL PRODUCT COMMUNICATIONS | 2011年 / 6卷 / 10期

关键词：

Pistacia lentiscus; carrageenan; edema; TNF-alpha; IL-6; ANTIOXIDANT ACTIVITIES; ANTIMICROBIAL ACTIVITY; PSORIATIC-ARTHRITIS; EXTRACTS; CHIA; RATS;

D O I：

暂无

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

The topical anti-inflammatory activity of essential oil of Pistacia lentiscus L. was studied using carrageenan induced rat paw edema and cotton pellet induced granuloma. The effect on serum tumor necrosis factor-alpha (TNF-alpha) and interleukin-6 (IL-6) in rats inserted with cotton pellet was also investigated. On topical application, the oil exhibited a significant decrease in paw edema. The oil also inhibited cotton pellet-induced granuloma, and reduced serum TNF-alpha and IL-6. It can be concluded that the essential oil of Pistacia lentiscus reduces leukocyte migration to the damaged tissue and exhibits anti-inflammatory activity.

引用

页码：1543 / 1544

页数：2

共 20 条

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