Gene transfer to hematopoietic stem cells: Implications for gene therapy of human disease

被引：0
作者：
Dunbar, CE
机构：
来源：
ANNUAL REVIEW OF MEDICINE | 1996年 / 47卷
关键词：
retrovirus; adeno-associated virus; gene expression; transplantation;
D O I：
暂无
中图分类号：
R-3 [医学研究方法]; R3 [基础医学];
学科分类号：
1001 ;
摘要：
Transfer of new genetic material to hematopoietic stem cells and expression of the gene product in daughter cells of various lineages is an exciting approach to the treatment of congenital and acquired human diseases. This review summarizes the current status of retroviral and adeno-associated viral vectors for gene transfer to human hematopoietic cells, including extensive preclinical data as well as preliminary results from ongoing clinical trials.
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页码：11 / 20
页数：10
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