Chemical immobilization of azido cellulose phenylcarbamate onto silica gel via Staudinger reaction and its application as a chiral stationary phase for HPLC

被引：22
|
作者：
Zhang, Sheng
Ong, Teng-Teng
Ng, Siu-Choon
Chan, Hardy Sze On
机构：
[1] Natl Univ Singapore, Dept Chem, Singapore 117543, Singapore
[2] Nanyang Technol Univ, Coll Engn, Div Chem & Bimol Engn, Singapore 639798, Singapore
来源：
TETRAHEDRON LETTERS | 2007年 / 48卷 / 31期
关键词：
D O I：
10.1016/j.tetlet.2007.05.167
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Azido cellulose phenylcarbamate (AzCPC) was synthesized regioselectively and chemically immobilized onto aminized silica gel to afford urea-bonded chiral stationary phases (CSPs). The obtained CSPs showed good enantioselectivity in HPLC towards various racemates using normal phase eluants (hexane/2-propanol, hexane/chloroform or hexane/2-propanol/chloroform). (c) 2007 Elsevier Ltd. All rights reserved.
引用
收藏
页码：5487 / 5490
页数：4
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