Strategies for the Design of HIV-1 Non-Nucleoside Reverse Transcriptase Inhibitors: Lessons from the Development of Seven Representative Paradigms

被引：119

作者：

Li, Dongyue ^{[1
]}

Zhan, Peng ^{[1
]}

De Clercq, Erik ^{[2
]}

Liu, Xinyong ^{[1
]}

机构：

[1] Shandong Univ, Sch Pharmaceut Sci, Dept Med Chem, Jinan 250012, Shandong, Peoples R China

[2] Katholieke Univ Leuven, Rega Inst Med Res, B-3000 Louvain, Belgium

来源：

JOURNAL OF MEDICINAL CHEMISTRY | 2012年 / 55卷 / 08期

基金：

高等学校博士学科点专项科研基金; 中国博士后科学基金; 中国国家自然科学基金;

关键词：

RESISTANT MUTANT VIRUSES; MEDICINAL CHEMISTRY; DRUG CANDIDATES; MOLECULAR HYBRIDIZATION; ANGSTROM RESOLUTION; ANTIVIRAL ACTIVITY; ETRAVIRINE TMC125; BROAD POTENCY; DAPY ANALOGS; WILD-TYPE;

D O I：

10.1021/jm200990c

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

[No abstract available]

引用

页码：3595 / 3613

页数：19

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