Plasma Ropivacaine Concentrations After Ultrasound-Guided Rectus Sheath Block in Patients Undergoing Lower Abdominal Surgery

被引：30

作者：

Wada, Morito ^{[1
]}

Kitayama, Masato ^{[1
]}

Hashimoto, Hiroshi ^{[1
]}

Kudo, Tsuyoshi ^{[1
]}

Kudo, Mihoko ^{[1
]}

Takada, Norikazu ^{[1
]}

Hirota, Kazuyoshi ^{[1
]}

机构：

[1] Hirosaki Univ, Grad Sch Med, Dept Anesthesiol, Hirosaki, Aomori 0368562, Japan

来源：

ANESTHESIA AND ANALGESIA | 2012年 / 114卷 / 01期

关键词：

PEDIATRIC ANESTHESIA; OLD TECHNIQUE; PLANE BLOCK; NERVE BLOCK; PHARMACOKINETICS; BUPIVACAINE; 0.5-PERCENT; CHILDREN;

D O I：

10.1213/ANE.0b013e3182367a68

中图分类号：

R614 [麻醉学];

学科分类号：

100217 ;

摘要：

A rectus sheath block can provide postoperative analgesia for midline incisions. However, information regarding the pharmacokinetics of local anesthetics used in this block is lacking. In this study, we detail the time course of ropivacaine concentrations after this block. Thirty-nine patients undergoing elective lower abdominal surgery were assigned to 3 groups receiving rectus sheath block with 20 mL of different concentrations of ropivacaine. Peak plasma concentrations were dose dependent, and there were no significant differences in the times to peak plasma concentrations. The present data also suggested a slower absorption kinetics profile for ropivacaine after rectus sheath block than other compartment blocks. (Anesth Analg 2012;114:230-2)

引用

页码：230 / 232

页数：3

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