Though the studied of the semi-rigid composite frame with steel plate shear wall, which under lateral cyclic loads, the structure of failure mode, hysteretic curves and deformation of critical sections were obtained. The internal forces transformation and energy dissipation mechanic, the interactive effect of the joint stiffness and steel plate of the structure were analyzed from energy dissipation capacity, load-carrying capacity, ductility, stress distribution and co-working mechanic of steel plate. The results showed that the structure has good ductility and energy dissipation capacity; the damage mode is local tearing of the infill plate, the tension-field action is obvious, with forming of plastic hinges at the bottom of column and PR connection, the failure mode of the specimen is in-plane flexural. The research provides a basis for engineering application and theoretical analysis of the structural system.