TCR repertoire and transcriptional signatures of circulating tumour-associated T cells facilitate effective non-invasive cancer detection

被引：0
作者：
Ji, Fansen [1 ,2 ]
Chen, Lin [2 ,3 ]
Chen, Zhizhuo [4 ]
Luo, Bin [3 ]
Wang, Yongwang [5 ]
Lan, Xun [1 ,2 ]
机构：
[1] Tsinghua Univ, MOE Key Lab, Tsinghua Peking Ctr Life Sci, Beijing, Peoples R China
[2] Tsinghua Univ, Sch Med, Beijing 100084, Peoples R China
[3] Tsinghua Univ, Sch Clin Med, Beijing Tsinghua Changgung Hosp, Gen Surg Dept, Beijing, Peoples R China
[4] Tsinghua Univ, Sch Life Sci, Beijing, Peoples R China
[5] Guilin Med Univ, Affiliated Hosp, Dept Anesthesiol, 15 Lequn Rd, Guilin 541001, Peoples R China
来源：
CLINICAL AND TRANSLATIONAL MEDICINE | 2022年 / 12卷 / 09期
关键词：
LIQUID BIOPSY; RECEPTOR REPERTOIRES; PERIPHERAL-BLOOD; RESPONSES; DIFFERENTIATION; IDENTIFICATION; LYMPHOCYTES; IMMUNOLOGY; LANDSCAPE; BLOCKADE;
D O I：
10.1002/ctm2.853
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
引用
收藏
页数：15
相关论文
共 89 条
  • [41] Lung cancer-associated T cell repertoire as potential biomarker for early detection of stage I lung cancer
    Li, Min
    Zhang, Chunliu
    Deng, Shichao
    Li, Li
    Liu, Shiqing
    Bai, Jing
    Xu, Yaping
    Guan, Yanfang
    Xia, Xuefeng
    Sun, Lunquan
    Carbone, David P.
    Hu, Chengping
    [J]. LUNG CANCER, 2021, 162 : 16 - 22
  • [42] T-cell receptor repertoire analysis for the diagnosis and treatment of solid tumor: A methodology and clinical applications
    Li, Na
    Yuan, Jiani
    Tian, Wenjia
    Meng, Lin
    Liu, Yongyu
    [J]. CANCER COMMUNICATIONS, 2020, 40 (10) : 473 - 483
  • [43] Liquid biopsy-based single-cell metabolic phenotyping of lung cancer patients for informative diagnostics
    Li, Ziming
    Wang, Zhuo
    Tang, Yin
    Lu, Xiang
    Chen, Jie
    Dong, Yu
    Wu, Baojun
    Wang, Chunying
    Yang, Liu
    Guo, Zhili
    Xue, Min
    Lu, Shun
    Wei, Wei
    Shi, Qihui
    [J]. NATURE COMMUNICATIONS, 2019, 10 (1)
  • [44] Sensitive and specific multi-cancer detection and localization using methylation signatures in cell-free DNA
    Liu, M. C.
    Oxnard, G. R.
    Klein, E. A.
    Swanton, C.
    Seiden, M., V
    [J]. ANNALS OF ONCOLOGY, 2020, 31 (06) : 745 - 759
  • [45] Deep learning-based prediction of the T cell receptor-antigen binding specificity
    Lu, Tianshi
    Zhang, Ze
    Zhu, James
    Wang, Yunguan
    Jiang, Peixin
    Xiao, Xue
    Bernatchez, Chantale
    Heymach, John, V
    Gibbons, Don L.
    Wang, Jun
    Xu, Lin
    Reuben, Alexandre
    Wang, Tao
    [J]. NATURE MACHINE INTELLIGENCE, 2021, 3 (10) : 864 - +
  • [46] Liquid Biopsy of Methylation Biomarkers in Cell-Free DNA
    Luo, Huiyan
    Wei, Wei
    Ye, Ziyi
    Zheng, Jiabo
    Xu, Rui-hua
    [J]. TRENDS IN MOLECULAR MEDICINE, 2021, 27 (05) : 482 - 500
  • [47] The integration of T cell migration, differentiation and function
    Masopust, David
    Schenkel, Jason M.
    [J]. NATURE REVIEWS IMMUNOLOGY, 2013, 13 (05) : 309 - 320
  • [48] Cytomegalovirus infection induces T-cell differentiation without impairing antigen-specific responses in Gambian infants
    Miles, David J. C.
    Sanneh, Mariama
    Holder, Beth
    Crozier, Sarah
    Nyamweya, Samuel
    Touray, Ebrima S.
    Palmero, Melba S.
    Zaman, Syed M. A.
    Rowland-Jones, Sarah
    van der Sande, Marianne
    Whittle, Hilton
    [J]. IMMUNOLOGY, 2008, 124 (03) : 388 - 400
  • [49] Prospective evaluation of 92 serum protein biomarkers for early detection of ovarian cancer
    Mukama, Trasias
    Fortner, Renee Turzanski
    Katzke, Verena
    Hynes, Lucas Cory
    Petrera, Agnese
    Hauck, Stefanie M.
    Johnson, Theron
    Schulze, Matthias
    Schiborn, Catarina
    Rostgaard-Hansen, Agnetha Linn
    Tjonneland, Anne
    Overvad, Kim
    Perez, Maria Jose Sanchez
    Crous-Bou, Marta
    Chirlaque, Maria-Dolores
    Amiano, Pilar
    Ardanaz, Eva
    Watts, Eleanor L.
    Travis, Ruth C.
    Sacerdote, Carlotta
    Grioni, Sara
    Masala, Giovanna
    Signoriello, Simona
    Tumino, Rosario
    Gram, Inger T.
    Sandanger, Torkjel M.
    Sartor, Hanna
    Lundin, Eva
    Idahl, Annika
    Heath, Alicia K.
    Dossus, Laure
    Weiderpass, Elisabete
    Kaaks, Rudolf
    [J]. BRITISH JOURNAL OF CANCER, 2022, 126 (09) : 1301 - 1309
  • [50] Identification of shared TCR sequences from T cells in human breast cancer using emulsion RT-PCR
    Munson, Daniel J.
    Egelston, Colt A.
    Chiotti, Kami E.
    Parra, Zuly E.
    Bruno, Tullia C.
    Moore, Brandon L.
    Nakano, Taizo A.
    Simons, Diana L.
    Jimenez, Grecia
    Yim, John H.
    Rozanov, Dmitri V.
    Falta, Michael T.
    Fontenot, Andrew P.
    Reynolds, Paul R.
    Leach, Sonia M.
    Borges, Virginia F.
    Kappler, John W.
    Spellman, Paul T.
    Lee, Peter P.
    Slansky, Jill E.
    [J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2016, 113 (29) : 8272 - 8277
123456789