Obesity, the Metabolic Syndrome, and Sexual Dysfunction in Men

被引：36

作者：

Esposito, K. ^{[1
]}

Giugliano, D. ^{[1
]}

机构：

[1] Univ Naples 2, Dept Geriatr & Metab Dis, Naples, Italy

来源：

CLINICAL PHARMACOLOGY & THERAPEUTICS | 2011年 / 90卷 / 01期

关键词：

ENDOTHELIAL PROGENITOR CELLS; MIDDLE-AGED MEN; ERECTILE-DYSFUNCTION; RISK-FACTORS; VASCULAR-DISEASE; TESTOSTERONE; METAANALYSIS; PREVALENCE; PREDICT;

D O I：

10.1038/clpt.2011.91

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

Our understanding of the relationships between obesity, metabolic syndrome, and erectile dysfunction (ED) has advanced significantly over the past decades. Increase in visceral adiposity and related risk factors are associated with a proinflammatory state that results in decreased nitric oxide (NO) availability and activity that is responsible, at least in part, for endothelial injury and dysfunction as well as for ED. The reduced testosterone levels associated with obesity and metabolic syndrome may contribute to ED.

引用

页码：169 / 173

页数：5

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