Lymphoepithelial carcinoma of the larynx

被引:19
作者
Coskun, BU [1 ]
Cinar, U [1 ]
Sener, BM [1 ]
Dadas, B [1 ]
机构
[1] Sisli Etfal Training & Res Hosp, Dept Otolaryngol, TR-34340 Istanbul, Turkey
关键词
lymphoepithelioma; larynx; EBV;
D O I
10.1016/j.anl.2004.11.014
中图分类号
R76 [耳鼻咽喉科学];
学科分类号
100213 ;
摘要
Lymphoepithelial carcinoma (LEC) of the larynx is a rare neoplasm; with a review of the literature having disclosed only 34 documented cases. This neoplasm seems to behave in a fashion reminiscent of nasopharyngeal carcinoma. In contrast to nasopharyngeal carcinoma, most cases have not been associated with Epstein-Barr virus (EBV). The diagnosis often requires immunohistochemistry or electron microscopy for confirmation. We describe a case of this tumor involving the supraglottis. The patient was treated with supraglottic laryngectomy and bilateral modified neck dissection. The histopathological study of the surgical specimen revealed an undifferentiated carcinoma with aspects of lymphoeptihelioma. The patient underwent radiotherapy and his 2-year follow-up showed no evidence of local or distant metastasis. (c) 2004 Elsevier Ireland Ltd. All rights reserved.
引用
收藏
页码:189 / 193
页数:5
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