Diels-Alder "Click" Reactions

被引：14
作者：
Gaso-Sokac, Dajana [1 ]
Stivojevic, Marija [2 ]
机构：
[1] Josip Juraj Strossmayer Univ Osijek, Fac Food Technol Osijek, Osijek, Croatia
[2] Josip Juraj Strossmayer Univ Osijek, Dept Chem, Osijek, Croatia
来源：
CURRENT ORGANIC CHEMISTRY | 2016年 / 20卷 / 21期
关键词：
Click reaction; Diels-Alder; hydrogels; inverse electron demand Diels-Alder reactions; polymers; AZIDE-ALKYNE CYCLOADDITION; STAR BLOCK-COPOLYMERS; REACTION STRATEGIES; TRANS-CYCLOOCTENE; CROSS-LINKING; CHEMISTRY; POLYMERS; TETRAZINE; CONJUGATION; HYDROGELS;
D O I：
10.2174/1385272820666160215235852
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
The Diels-Alder reactions can be classified as click reactions because of their simplicity and high yields. The Diels-Alder click reactions have been used for the preparation of complex macromolecules, such as hydrogels and polymers and also for labeling of various biological targets. This review summarizes the recent application of Diels-Alder click reactions in hydrogel synthesis, polymer and material science and also medicinal application of Diels-Alder click reaction.
引用
收藏
页码：2211 / 2221
页数：11
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共 77 条
  • [1] A comparative study of bioorthogonal reactions with azides
    Agard, Nicholas J.
    Baskin, Jeremy M.
    Prescher, Jennifer A.
    Lo, Anderson
    Bertozzi, Carolyn R.
    [J]. ACS CHEMICAL BIOLOGY, 2006, 1 (10) : 644 - 648
  • [2] A strain-promoted [3+2] azide-alkyne cycloaddition for covalent modification of blomolecules in living systems
    Agard, NJ
    Prescher, JA
    Bertozzi, CR
    [J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2004, 126 (46) : 15046 - 15047
  • [3] Poly(ethylene glycol)-Thioxanthone Prepared by Diels-Alder Click Chemistry as One-Component Polymeric Photoinitiator for Aqueous Free-Radical Polymerization
    Akat, Hakan
    Gacal, Burcin
    Balta, Demet Karaca
    Arsu, Nergis
    Yagci, Yusuf
    [J]. JOURNAL OF POLYMER SCIENCE PART A-POLYMER CHEMISTRY, 2010, 48 (10) : 2109 - 2114
  • [4] Synthesis of an ABCD 4-Miktoarm Star Quaterpolymer Through a Diels-Alder Click Reaction
    Altintas, Ozcan
    Hizal, Gurkan
    Tunca, Umit
    [J]. DESIGNED MONOMERS AND POLYMERS, 2009, 12 (01) : 83 - 98
  • [5] Patterned Surface Derivatization Using Diels-Alder Photoclick Reaction
    Arumugam, Selvanathan
    Popik, Vladimir V.
    [J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2011, 133 (39) : 15730 - 15736
  • [6] "Clicking" Polymers or Just Efficient Linking: What Is the Difference?
    Barner-Kowollik, Christopher
    Du Prez, Filip E.
    Espeel, Pieter
    Hawker, Craig J.
    Junkers, Tanja
    Schlaad, Helmut
    Van Camp, Wim
    [J]. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2011, 50 (01) : 60 - 62
  • [7] Tetrazine ligation: Fast bioconjugation based on inverse-electron-demand Diels-Alder reactivity
    Blackman, Melissa L.
    Royzen, Maksim
    Fox, Joseph M.
    [J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2008, 130 (41) : 13518 - +
  • [8] Synthesis of Comb Polymers via Grafting-Onto Macromolecules Bearing Pendant Diene Groups via the Hetero-Diels-Alder-RAFT Click Concept
    Bousquet, Antoine
    Barner-Kowollik, Christopher
    Stenzel, Martina H.
    [J]. JOURNAL OF POLYMER SCIENCE PART A-POLYMER CHEMISTRY, 2010, 48 (08) : 1773 - 1781
  • [9] Heterograft Brush Copolymers via Romp and Triple Click Reaction Strategies Involving CuAAC, Diels-Alder, and Nitroxide Radical Coupling Reactions
    Cakir, Nese
    Yavuzarslan, Merve
    Durmaz, Hakan
    Hizal, Gurkan
    Tunca, Umit
    [J]. JOURNAL OF POLYMER SCIENCE PART A-POLYMER CHEMISTRY, 2013, 51 (04) : 899 - 907
  • [10] A NOVEL NONIONIC HYDROGEL FROM 2-METHYL-2-OXAZOLINE .4. REVERSIBLE GELATION OF POLYOXAZOLINE BY MEANS OF DIELS-ALDER REACTION
    CHUJO, Y
    SADA, K
    SAEGUSA, T
    [J]. MACROMOLECULES, 1990, 23 (10) : 2636 - 2641
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