The addition of a stilbene optical brightener, Tinopal LPW, at 1% concentration (wt:wt) significantly reduced the LC50 of the beet armyworm nuclear polyhedrosis virus (SeMNPV) from 2.9 PIB/mm(2) to 0.02 PIB/mm(2). Moreover, the LT50 of SeMNPV was reduced Ly 34% by the addition of Tinopal LPW. Seven other structurally related stilbene brighteners M ere also tested as viral enhancers. Five of these brighteners (Tinopal LPW, Blankophor BBH, Blankophor HRS, Blankophor P167, and Blankophor RKH) reduced LD(50)s, whereas three brighteners (Blankophor BSU, Blankophor DML, and Blankophor LPG) had little effect. Among the active brighteners, LC(50)s were reduced by 10.5-fold (Blankophor P167). 52.4-fold (Blankophor RKH), 87.3-fold Tinopal LPW, 131-fold (Blankophor BBH), and > 400-fold (Blankophor HRS). LT(50)s M ere also decreased by the addition of Blankophor BBH, Blankophor P167. and Blankophor RKH, but were increased by the addition of Blankophor BSU. Blankophor DMLO, and Blankophor LPG to SeMNPV suspensions.