Alkyl-substituted 1,1'-Dihydroxy-2,2'bimidazoles: Reactions with Methyl Iodide and Trimethyl Phosphite

被引：3
|
作者：
Os'kina, I. A. [1 ]
Tikhonov, A. Ya [1 ]
机构：
[1] Russian Acad Sci, Vorozhtsov Novosibirsk Inst Organ Chem, Siberian Branch, Novosibirsk 630090, Russia
来源：
RUSSIAN JOURNAL OF ORGANIC CHEMISTRY | 2020年 / 56卷 / 02期
关键词：
1; 1'-dihydroxy-2; 2'-biimidazoles; 2; methylation; reduction;
D O I：
10.1134/S107042802001027X
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
The alkylation of alkyl-substituted 1,1'-dihydroxy-2,2'-biimidazoles with an equimolar amount of methyl iodide occurs exclusively at the imidazole nitrogen atom, while with a three-fold excess of methyl iodide, both the imidazole nitrogen atom and two hydroxy groups are involved in alkylation. The reaction of 1,1'-dihydroxy-2,2'-biimidazoles with P(OMe)(3) forms the corresponding 2,2'-biimidazoles.
引用
收藏
页码：339 / 342
页数：4
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