Physical Function and Disability in Older Adults with Diabetes

被引:38
作者
de Rekeneire, Nathalie [1 ]
Volpato, Stefano [2 ]
机构
[1] Yale Univ, Sch Med, Dept Internal Med, Sect Geriatr, New Haven, CT 06520 USA
[2] Univ Ferrara, UO Med Interna Univ, Azienda Osped Univ Ferrara, Sect Internal Med Gerontol & Clin,Dept Med Sci, I-44124 Ferrara, Italy
关键词
Diabetes; Functional limitation; Disability; Muscle strength; Aging; NUTRITION EXAMINATION SURVEY; LOWER-EXTREMITY FUNCTION; MUSCLE STRENGTH; NATIONAL-HEALTH; WOMENS HEALTH; PERIPHERAL NEUROPATHY; GLYCEMIC CONTROL; HIGHER RISK; PERFORMANCE; ASSOCIATION;
D O I
10.1016/j.cger.2014.08.018
中图分类号
R592 [老年病学]; C [社会科学总论];
学科分类号
03 ; 0303 ; 100203 ;
摘要
Functional decline and physical disability are an important clinical and public health problem in older adults because they are associated with loss of independence, nursing home admission, and mortality. Several impairments and comorbidities related to or associated with diabetes are potential disabling conditions that could account for the excess risk of disability. But in most studies, no single condition explains this association. Accelerated loss of muscle strength is a potential mediator in the disabling effect of diabetes. Because some diabetes-related comorbidities are potential modifiable risk factors, preventing and reducing the excess risk of disability associated with diabetes needs further study.
引用
收藏
页码:51 / +
页数:16
相关论文
共 72 条
[1]   The prevalence of comorbid depression in adults with diabetes - A meta-analysis [J].
Anderson, RJ ;
Freedland, KE ;
Clouse, RE ;
Lustman, PJ .
DIABETES CARE, 2001, 24 (06) :1069-1078
[2]   Predictors of combined cognitive and physical decline [J].
Atkinson, HH ;
Cesari, M ;
Kritchevsky, SB ;
Penninx, BWJH ;
Fried, LP ;
Guralnik, JM ;
Williamson, JD .
JOURNAL OF THE AMERICAN GERIATRICS SOCIETY, 2005, 53 (07) :1197-1202
[3]   The relation of markers of inflammation to the development of glucose disorders in the elderly - The cardiovascular health study [J].
Barzilay, JI ;
Abraham, L ;
Heckbert, SR ;
Cushman, M ;
Kuller, LH ;
Resnick, HE ;
Tracy, RP .
DIABETES, 2001, 50 (10) :2384-2389
[4]   Muscle protein anabolism in type 2 diabetes [J].
Bassil, Maya S. ;
Gougeon, Rejeanne .
CURRENT OPINION IN CLINICAL NUTRITION AND METABOLIC CARE, 2013, 16 (01) :83-88
[5]   Predictors of nursing facility admission: A 12-year epidemiological study in the United States [J].
Bharucha, AJ ;
Pandav, R ;
Shen, CY ;
Dodge, HH ;
Ganguli, M .
JOURNAL OF THE AMERICAN GERIATRICS SOCIETY, 2004, 52 (03) :434-439
[6]   Risk of dementia in diabetes mellitus: a systematic review [J].
Biessels, GJ ;
Staekenborg, S ;
Brunner, E ;
Brayne, C ;
Scheltens, P .
LANCET NEUROLOGY, 2006, 5 (01) :64-74
[7]   Prevalence of diabetes and effect on quality of life in older French living in the community: The PAQUID epidemiological survey [J].
BourdelMarchasson, I ;
Dubroca, B ;
Manciet, G ;
Decamps, A ;
Emeriau, JP ;
Dartigues, JF .
JOURNAL OF THE AMERICAN GERIATRICS SOCIETY, 1997, 45 (03) :295-301
[8]   Projection of diabetes burden through 2050 - Impact of changing demography and disease prevalence in the US [J].
Boyle, JP ;
Honeycutt, AA ;
Narayan, KMV ;
Hoerger, TJ ;
Geiss, LS ;
Chen, H ;
Thompson, TJ .
DIABETES CARE, 2001, 24 (11) :1936-1940
[9]   A PROSPECTIVE-STUDY OF LONG-TERM CARE INSTITUTIONALIZATION AMONG THE AGED [J].
BRANCH, LG ;
JETTE, AM .
AMERICAN JOURNAL OF PUBLIC HEALTH, 1982, 72 (12) :1373-1379
[10]   Longitudinal predictors of reduced mobility and physical disability in patients with type 2 diabetes - The Fremantle Diabetes Study [J].
Bruce, DG ;
Davis, WA ;
Davis, TME .
DIABETES CARE, 2005, 28 (10) :2441-2447