Obesity, transplantation, and bariatric surgery: An evolving solution for a growing epidemic

被引：55

作者：

Diwan, Tayyab S. ^{[1
]}

Lee, Tiffany C. ^{[1
]}

Nagai, Shunji ^{[2
]}

Benedetti, Enrico ^{[3
]}

Posselt, Andrew ^{[4
]}

Bumgardner, Ginny ^{[5
]}

Noria, Sabrena ^{[5
]}

Whitson, Bryan A. ^{[5
]}

Ratner, Lloyd ^{[6
]}

Mason, David ^{[7
]}

Friedman, Jon ^{[8
]}

Woodside, Kenneth J. ^{[9
]}

Heimbach, Julie ^{[10
]}

机构：

[1] Univ Cincinnati, Cincinnati, OH 45221 USA

[2] Henry Ford Hosp, Detroit, MI 48202 USA

[3] Univ Illinois, Chicago, IL USA

[4] Univ Calif San Francisco, San Francisco, CA 94143 USA

[5] Ohio State Univ, Columbus, OH 43210 USA

[6] Columbia Univ, Med Ctr, New York, NY USA

[7] Baylor Med Ctr, Dallas, TX USA

[8] OptumHealth, Cypress, CA USA

[9] Univ Michigan, Ann Arbor, MI 48109 USA

[10] Mayo Clin, Rochester, MN USA

来源：

AMERICAN JOURNAL OF TRANSPLANTATION | 2020年 / 20卷 / 08期

关键词：

clinical decision-making; clinical research; practice; obesity; organ transplantation in general; recipient selection; BODY-MASS INDEX; LAPAROSCOPIC SLEEVE GASTRECTOMY; COMBINED LIVER-TRANSPLANTATION; INDEPENDENT RISK-FACTOR; LONG-TERM OUTCOMES; KIDNEY-TRANSPLANTATION; WEIGHT-LOSS; NONALCOHOLIC STEATOHEPATITIS; METABOLIC SYNDROME; GASTRIC BYPASS;

D O I：

10.1111/ajt.15784

中图分类号：

R61 [外科手术学];

学科分类号：

摘要：

The increasing obesity epidemic has major implications in the realm of transplantation. Patients with obesity face barriers in access to transplant and unique challenges in perioperative and postoperative outcomes. Because of comorbidities associated with obesity, along with the underlying end-stage organ disease leading to transplant candidacy, these patients may not even be referred for transplant evaluation, much less be waitlisted or actually undergo transplant. However, the use of bariatric surgery in this population can help optimize the transplant candidacy of patients with obesity and end-stage organ disease and improve perioperative and postoperative outcomes. We review the impact of obesity on kidney, liver, and cardiothoracic transplant candidates and recipients and explore potential interventions to address obesity in these populations.

引用

页码：2143 / 2155

页数：13

共 122 条

[41] Combined Liver Transplantation and Gastric Sleeve Resection for Patients With Medically Complicated Obesity and End-Stage Liver Disease [J].