Obesity, transplantation, and bariatric surgery: An evolving solution for a growing epidemic

被引:55
作者
Diwan, Tayyab S. [1 ]
Lee, Tiffany C. [1 ]
Nagai, Shunji [2 ]
Benedetti, Enrico [3 ]
Posselt, Andrew [4 ]
Bumgardner, Ginny [5 ]
Noria, Sabrena [5 ]
Whitson, Bryan A. [5 ]
Ratner, Lloyd [6 ]
Mason, David [7 ]
Friedman, Jon [8 ]
Woodside, Kenneth J. [9 ]
Heimbach, Julie [10 ]
机构
[1] Univ Cincinnati, Cincinnati, OH 45221 USA
[2] Henry Ford Hosp, Detroit, MI 48202 USA
[3] Univ Illinois, Chicago, IL USA
[4] Univ Calif San Francisco, San Francisco, CA 94143 USA
[5] Ohio State Univ, Columbus, OH 43210 USA
[6] Columbia Univ, Med Ctr, New York, NY USA
[7] Baylor Med Ctr, Dallas, TX USA
[8] OptumHealth, Cypress, CA USA
[9] Univ Michigan, Ann Arbor, MI 48109 USA
[10] Mayo Clin, Rochester, MN USA
关键词
clinical decision-making; clinical research; practice; obesity; organ transplantation in general; recipient selection; BODY-MASS INDEX; LAPAROSCOPIC SLEEVE GASTRECTOMY; COMBINED LIVER-TRANSPLANTATION; INDEPENDENT RISK-FACTOR; LONG-TERM OUTCOMES; KIDNEY-TRANSPLANTATION; WEIGHT-LOSS; NONALCOHOLIC STEATOHEPATITIS; METABOLIC SYNDROME; GASTRIC BYPASS;
D O I
10.1111/ajt.15784
中图分类号
R61 [外科手术学];
学科分类号
摘要
The increasing obesity epidemic has major implications in the realm of transplantation. Patients with obesity face barriers in access to transplant and unique challenges in perioperative and postoperative outcomes. Because of comorbidities associated with obesity, along with the underlying end-stage organ disease leading to transplant candidacy, these patients may not even be referred for transplant evaluation, much less be waitlisted or actually undergo transplant. However, the use of bariatric surgery in this population can help optimize the transplant candidacy of patients with obesity and end-stage organ disease and improve perioperative and postoperative outcomes. We review the impact of obesity on kidney, liver, and cardiothoracic transplant candidates and recipients and explore potential interventions to address obesity in these populations.
引用
收藏
页码:2143 / 2155
页数:13
相关论文
共 122 条
[1]   Liver Transplantation for Nonalcoholic Steatohepatitis The New Epidemic [J].
Agopian, Vatche G. ;
Kaldas, Fady M. ;
Hong, Johnny C. ;
Whittaker, Meredith ;
Holt, Curtis ;
Rana, Abbas ;
Zarrinpar, Ali ;
Petrowsky, Henrik ;
Farmer, Douglas ;
Yersiz, Hasan ;
Xia, Victor ;
Hiatt, Jonathan R. ;
Busuttil, Ronald W. .
ANNALS OF SURGERY, 2012, 256 (04) :624-633
[2]   Obesity Is Associated with Driveline Infection of Left Ventricular Assist Devices [J].
Akay, Mehmet H. ;
Nathan, Sriram S. ;
Radovancevic, Rajko ;
Poglajen, Gregor ;
Jezovnik, Mateja K. ;
Candelaria, Isabella N. ;
Averill, Barbara L. ;
Patel, Manish K. ;
Kar, Biswajit ;
Gregoric, Igor D. .
ASAIO JOURNAL, 2019, 65 (07) :678-682
[3]   Gastric Bypass After Liver Transplantation [J].
Al-Nowaylati, Abdl-Rawf ;
Al-Haddad, Benjamin J. S. ;
Dorman, Rob B. ;
Alsaied, Osama A. ;
Lake, John R. ;
Chinnakotla, Srinath ;
Slusarek, Bridget M. ;
Sampson, Barbara K. ;
Ikramuddin, Sayeed ;
Buchwald, Henry ;
Leslie, Daniel B. .
LIVER TRANSPLANTATION, 2013, 19 (12) :1324-1329
[4]   The impact of recipient body mass index on survival after lung transplantation [J].
Allen, Jeremiah G. ;
Arnaoutakis, George J. ;
Weiss, Eric S. ;
Merlo, Christian A. ;
Conte, John V. ;
Shah, Ashish S. .
JOURNAL OF HEART AND LUNG TRANSPLANTATION, 2010, 29 (09) :1026-1033
[5]  
Andrews LM, 2017, TRANSPLANT DIRECT, V3, DOI 10.1097/TXD.0000000000000644
[6]   Bariatric surgery in patients with interstitial lung disease [J].
Ardila-Gatas, Jessica ;
Sharma, Gautam ;
Hanipah, Zubaidah Nor ;
Tu, Chao ;
Brethauer, Stacy A. ;
Aminian, Ali ;
Tolle, Leslie ;
Schauer, Philip R. .
SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES, 2019, 33 (06) :1952-1958
[7]   The Incidence and Risk Factors of Hepatocellular Carcinoma in Patients with Nonalcoholic Steatohepatitis [J].
Ascha, Mustafa S. ;
Hanouneh, Ibrahim A. ;
Lopez, Rocio ;
Tamimi, Tarek Abu-Rajab ;
Feldstein, Ariel F. ;
Zein, Nizar N. .
HEPATOLOGY, 2010, 51 (06) :1972-1978
[8]  
BAKER AM, 1992, J HEART LUNG TRANSPL, V11, P1156
[9]   Low, rather than high, body mass index confers increased risk for post-liver transplant death and graft loss: Risk modulated by model for end-stage liver disease [J].
Bambha, Kiran M. ;
Dodge, Jennifer L. ;
Gralla, Jane ;
Sprague, David ;
Biggins, Scott W. .
LIVER TRANSPLANTATION, 2015, 21 (10) :1286-1294
[10]   Effects of body size and body composition on survival in hemodialysis patients [J].
Beddhu, S ;
Pappas, LM ;
Ramkumar, N ;
Samore, M .
JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY, 2003, 14 (09) :2366-2372